ĐÁNH GIÁ TÌNH HÌNH SỬ DỤNG KHÁNG SINH TRONG ĐỢT CẤP BỆNH PHỔI TẮC NGHẼN MẠN TÍNH TẠI MỘT BỆNH VIỆN Ở KHU VỰC ĐỒNG BẰNG SÔNG CỬU LONG NĂM 2022 – 2023

Abstract

Background: According to the 2018 guideline for diagnosis and treatment of COPD of the Ministry of Health of Vietnam, antibiotics should be prescribed in patients with moderate or severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD). However, appropriate use of antibiotics is an issue that needs attention in the current situation of antibiotic resistance. Objectives: Determine the characteristics of antibiotic use and the rate of appropriate antibiotic use in AECOPD. Materials and methods: Cross-sectional of 224 inpatients with AECOPD and receiving antibiotics at a hospital in the Mekong Delta region during the period from 10/2022 to 03/2023. Results: Cephalosporin is the most commonly used antibiotic group (47.9%), the initial antibiotic regimen is mainly combination (91.1%). There are 93.3% of medical records with reasonable antibiotic choices, 72.8% of medical records with appropriate doses of antibiotics, 64.3% of medical records with reasonable frequency of antibiotics, 64,7% of medical records do not have serious antibiotic drug interactions and the overall rate of appropriate antibiotic use is 40.6%. Conclusions: The results of the study provide an objective perspective on the appropriate use of antibiotics in exacerbations of COPD from a clinical pharmacy perspective. This helps to use antibiotics more reasonably, effectively and safely.