MỐI LIÊN QUAN GIỮA TĂNG TRIGLYCERID MÁU VỚI MỨC ĐỘ NẶNG THEO ATLANTA SỬA ĐỔI VÀ TÌNH TRẠNG HOẠI TỬ TỤY THEO BALTHAZAR

Abstract

Objective: To determine the relationship between elevated blood triglyceride levels and the severity of acute pancreatitis as well as pancreatic necrosis. Subjects and Methods: The study was conducted on two groups of patients with acute pancreatitis: Group 1 (5.7-11.3 mmol/l) and Group 2 (≥ 11.3 mmol/l). Multivariate analysis and logistic regression were used to compare the severity of pancreatitis and pancreatic necrosis between the two groups. Results: Severe Acute Pancreatitis: Group 2 (≥ 11.3 mmol/l) had a higher rate of severe acute pancreatitis compared to Group 1 (31.4% vs. 19.6%), indicating that elevated triglyceride levels are associated with increased disease severity. Pancreatic Necrosis: Group 2 had a higher rate of severe pancreatic necrosis (29.4% vs. 19.6%), with a strong correlation between triglyceride levels and Balthazar score (r = 0.59, p < 0.001). Multivariate Analysis: Elevated triglyceride levels were found to be an independent predictor of severe acute pancreatitis (OR = 1.9, p = 0.01) and severe pancreatic necrosis (OR = 3.5, p < 0.001). Conclusion: High blood triglyceride levels are closely associated with increased severity and more significant pancreatic damage, requiring careful monitoring and control.