XÁC ĐỊNH TỶ LỆ NHIỄM MYCOBACTERIUM TUBERCULOSIS BẰNG KỸ THUẬT GENEXPERT TẠI BỆNH VIỆN TRUNG ƯƠNG QUÂN ĐỘI 108 NĂM 2023

Abstract

Tuberculosis, caused by Mycobacterium tuberculosis, remains one of the leading causes of mortality from infectious diseases globally. Vietnam ranks among the countries with the highest TB infection rates. Objectives and methods: This cross-sectional study aimed to assess the prevalence of M. tuberculosis infection and rifampicin resistance, and risk factors using the GeneXpert diagnostic system at the 108 Military Central Hospital. Results: Of 875 patients tested, the prevalence of M. tuberculosis infection was 24.8%, with a rifampicin resistance rate of 7.37%. The highest infection rates were observed in men and individuals under 30. Respiratory specimens were more effective for TB detection compared to non-respiratory specimens. Factors such as age, gender, specimen type, and geographic location were not associated significantly with rifampicin-resistance of M. tuberculosis. Conclusion: This study highlights the critical need for stringent management of antibiotic use in TB treatment to curb infection rates and the emergence of drug-resistant strains.