ĐÁNH GIÁ KẾT QUẢ SAU MỔ CẮT KHỐI TÁ TUỴ ĐIỀU TRỊ U ĐẶC GIẢ NHÚ ĐẦU TỤY TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC

Abstract

Objective: To evaluate the early and long-term outcomes of patients after pancreaticoduodenectomy for pseudopapillary solid tumors in the pancreatic head. Methods: A retrospective study of all patients with pancreaticoduodenectomy for pseudopapillary solid tumors at the pancreatic head in Viet Duc Hospital from January 2014 to October 2020. Results: There were 34 patients with pancreaticoduodenectomy for pseudopapillary solid tumors at the pancreatic head in the study, with an average age of 30.9 ± 13.7 years, of which 88.2% were female. Epigastric pain accounted for the highest rate of 70.5%, and asymptomatic patients with incidental disease diagnosis accounted for 29.4%. Computed tomography showed that the tumor had clear boundaries in 90.9%, had a tumor capsule in 75.7%, had tissue and fluid structures in 78.8%, had heterogenous and increasing contrast enhancement in the venous phase in 78.8%, had a dilated common bile duct in 3%, and a dilated Wirsung duct in 6.1%. All patients underwent open surgery to perform the pancreaticoduodenectomy, of which 58.8% had a pancreaticoenteric anastomosis, and 41.2% had a pancreaticogastric anastomosis. The average surgical time was 307 ± 68 minutes, and 64.7% did not require blood transfusion. The average hospital stay was 12.4 ± 3.2 days. The postoperative mortality rate was 0%, postoperative bleeding 2.9%, and 2.9% for pancreatic fistula. The 5-year, 10-year survival rate after surgery was 96.4%, and the 5-year, 10-year recurrence-free rate was 92.8%. 82.1% of patients had good quality of life after surgery. Conclusion: Pancreatoduodenectomy for solid pseudopapillary tumor at pancreatic head was performed safely with low complication rates. Overall survival and disease-free survival rates after 5 and 10 years are high and postoperative quality of life is good.