Article Sidebar

pdf
Date Published: 21/04/2025
Abstract Views: 89
Views pdf: 41
DOI: https://doi.org/10.51298/vmj.v549i1.13537
Issue
Vol. 549 No. 1 (2025)
Section
Các bài báo
How to Cite
Đào Thị, T., & Trần Thị Kiều, M. (2025). CHARACTERITICS OF COAGULATION TESTS IN PATIENTS WITH PREGNANCY IN NIHBT FROM 2023 TO 2024. Vietnam Medical Journal, 549(1). https://doi.org/10.51298/vmj.v549i1.13537

CHARACTERITICS OF COAGULATION TESTS IN PATIENTS WITH PREGNANCY IN NIHBT FROM 2023 TO 2024

Thiết Đào Thị, My Trần Thị Kiều

Main Article Content

Abstract

Objective: To evaluate the characteritics of coagulation tests in patients with pregnancy. Patients and methods: This prospective study included 182 pregnant woman in NIHBT for the first time due to abnormal peripheral blood cell indices or increased D-dimer in the period 2023 – 2024. Results: Platelet count decreased while fibrinogen concentration and prothrombin ratio increase with increasing gestational age. Median FM concentrations was 77,5 ± 71,9µg/ml, the rate of patients with elevated FM was 58%. 94% of patients increased D-dimer level. And all patients in 3thtrimester of pregnancy had high level of D-dimer.

Article Details

Keywords

coagulation test, hypercoagulable state, pregnancy

References

1. Katz D, Beilin Y. Disorders of coagulation in pregnancy. Br J Anaesth. 2015;115 Suppl 2:ii75-88. doi:10.1093/bja/aev374
2. Mangla A, Hamad H. Thrombocytopenia in Pregnancy. In: StatPearls. StatPearls Publishing; 2024. Accessed September 29, 2024. http://www. ncbi.nlm.nih.gov/books/NBK547705/
3. Szecsi PB, Jørgensen M, Klajnbard A, Andersen MR, Colov NP, Stender S. Haemostatic reference intervals in pregnancy. Thromb Haemost. 2010;103(4):718-727. doi:10. 1160/TH09-10-0704
4. Joly B, Barbay V, Borg JY, Le Cam-Duchez V. Comparison of markers of coagulation activation and thrombin generation test in uncomplicated pregnancies. Thromb Res. 2013;132(3):386-391. doi:10.1016/j.thromres.2013.07.022
5. Hansen AT, Andreasen BH, Salvig JD, Hvas AM. Changes in fibrin D-dimer, fibrinogen, and protein S during pregnancy. Scand J Clin Lab Invest. 2011;71(2): 173-176. doi:10.3109/ 00365513.2010.545432
6. Onishi H, Kaniyu K, Iwashita M, Tanaka A, Watanabe T. Fibrin monomer complex in normal pregnant women: a potential thrombotic marker in pregnancy. Ann Clin Biochem. 2007;44(Pt 5):449-454. doi:10.1258/000456307781646076
7. Wang M, Lu S, Li S, Shen F. Reference intervals of D-dimer during the pregnancy and puerperium period on the STA-R evolution coagulation analyzer. Clin Chim Acta. 2013;425: 176-180. doi:10.1016/j.cca.2013.08.006
8. Kawamura M, Fukuda N, Suzuki A, et al. Use of fibrin monomer complex for screening for venous thromboembolism in the late pregnancy and post-partum period. Journal of Obstetrics and Gynaecology Research. 2014;40(3):700-704. doi:10.1111/jog.12245