THE CLINICAL EFFECTS OF ADVANCED PLATELET-RICH FIBRIN COMBINED WITH XENOGENIC BONE IN PERIODONTAL TREATMENT

Mẹo Nguyễn

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Abstract

Purpose: Periodontitis is a common oral disease and the leading cause of tooth loss. The aim of the study is to evaluate the clinical effects of advanced platelet-rich fibrin (A-PRF) and xenogenic bone substitute material (XBSM) in periodontal treatment. Materials and methods: 46 intrabony defects of 23 patients were randomly divided into 2 groups: test group (A-PRF-XBSM + collagen membrane + PRF membrane) and control group (XBSM + collagen membrane). The following clinical parameters were recorded at baseline (T0) and 3 months (T3) after surgery: plaque index (PlI), gingival index (GI), gingival recession (GR) pocket depth (PD) and clinical attachment level (CAL). Result: Significantly greater mean reduction of PD and CAL gain was observed in test group in comparison with control group at 3 months (p < 0,05). Conclusion: The use of advanced platelet-rich fibrin and xenogenic bone improved periodontal pocket depth and clinical attachment loss, might provide potential advantages for periodontal tissue regeneration.

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References

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