CHỈ SỐ TRIGLYCERID - GLUCOSE ỨNG VỚI MỨC NGUY CƠ BIẾN CỐ TIM MẠCH THEO THANG NGUY CƠ FRAMINGHAM VÀ SCORE_VN

Abstract

Background: Patients (PTs) with atherosclerosis are at high risk of major adverse cardiovascular events, including cardiovascular death, stroke, and non-fatal myocardial infarction. The Triglyceride - Glucose (TyG) index is believed to be associated with future cardiovascular events. Objectives: To determine the Triglyceride - Glucose Index cut-off point corresponding to intermediate and high cardiovascular risk groups according to the Framingham Risk Score (FRS) and SCORE_VN in individuals with cardiometabolic risk factors. Subjects and research methods: A descriptive cross-sectional study was performed on 223 patients with cardiometabolic risk factors, aged 40 to 69, at Cardiology Outpatient Clinic, University Medical Center Ho Chi Minh City, Campus 1, from September to December 2024. Results: The area under the curve (AUC) of the TyG index for FRS and SCORE_VN was 0.74 (95% CI: 0.67 – 0.81; p < 0.001) and 0.67 (95% CI: 0.60 – 0.74; p < 0.001), respectively. The cut-off points of the TyG index for the intermediate and high cardiovascular risk groups according to FRS and SCORE_VN were both 9.0 (sensitivity 65.0%, specificity 72.4%, positive predictive value 46.4%, negative predictive value 84.9% for FRS and sensitivity 54.2%, specificity 74.8%, positive predictive value 61.9%, negative predictive value 68.3% for SCORE_VN). Conclusion: The TyG index has a fair value in predicting the risk of future cardiovascular events according to FRS and SCORE_VN with the TyG cut-off point at 9.0.