EVALUATE THE EFFICACY OF TREATMENT OF PROLONGED DIARRHEA IN CHILDREN AT THE VIETNAM NATIONAL CHILDREN’S HOSPITAL

Hà Nguyễn Thị Việt, Bách Nguyễn Trọng, Quỳnh Hoàng Ngọc

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Abstract

Prolonged diarrhea is classified according to its onset and duration of 8–13 days, affecting the child's absorption of water, electrolytes and nutrition. Aim: To evaluate the efficacy of treatment of prolonged diarrhea in children 6 - 24 months old at the Department of Gastroenterology, National Children's Hospital. Materials and methods: a prospective study was conducted on 79 children aged 6-24 months diagnosed with prolonged diarrhea at the National Children's Hospital from July 1, 2023 - June 30, 2024. Results: The mean age of the children was 10.2 ± 4.2 months. The boys/girls ratio was 1.8/1. 100% of children received antibiotics and oral rehydration solution, 30.4% received electrolyte rehydration according to plan B. The prevalence of children receiving probiotic and zinc supplements was 97.5% and 45.6%, respectively. Initial antibiotics of choice for children were cefixime (58.2%) and azithromycin (32.9%). After 3 days, 69.7% of children were switched antibiotics from oral to intravenous route. 48.1% received ceftriaxone and 16.5% received a combination of two antibiotics. The hospitalization time was 6.9 ± 2.7 days. At the time of discharge, symptoms of fever, vomiting, diarrhea and dehydration were significantly improved, and stool tests returned to normal. The percentage of children with anorexia and anal inflammation was still high at the rate of 50.6% and 63.3%, respectively. Conclusion: Prolonged infectious diarrhea is a common problem in children that requires a combination of treatment measures, in which appropriate use of antibiotics, rehydration, zinc supplementation and probiotics are important treatment measures.

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References

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