THE SIGNIFICANCE OF MEASURING HEMOGLOBIN CONTENT IN RETICULOCYTE RED BLOOD CELLS (RET-HE) IN DIAGNOSING LATENT IRON DEFICIENCY IN BLOOD DONORS AT TAY NGUYEN REGIONAL GENERAL HOSPITAL

Nhung Nguyễn Thị Hồng, Phượng Nguyễn Thị Bích

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Abstract

Objectives: Study on Detecting Latent Iron Deficiency in Blood Donors Using the Ret-He Test. Patients and methods: Descriptive Cross-Sectional Study. Results: Among 321 blood donors without anemia (Hb ≥ 120 g/l), 72 cases (22.4%) of latent iron deficiency were detected according to the gold standard. Of these 72 cases, the cutoff point of Ret-He <30 pg accurately diagnosed 52 individuals and missed 20 cases. Therefore, the sensitivity of Ret-He is 72.2%. Among 249 blood donors with normal iron stores (according to the gold standard), Ret-He accurately diagnosed 234 cases of LID, missing 15 cases. Thus, the specificity of Ret-He is 94.0%. The area under the ROC curve is 0.83. Conclusion: The Ret-He test has high sensitivity and specificity in detecting early iron deficiency in blood donors.

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References

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