EMERGENCE QUALITY OF DESFLURANE VERSUS SEVOFLURANE IN ENDOSCOPIC SINUS SURGERY

Hiệu Đặng Minh, Trí Lê Hữu, Hùng Hà Quốc, Nghi Nguyễn Thị, Vũ Phan Tôn Ngọc, Dung Nguyễn Thị Phương

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Abstract

Background: Low-flow anesthesia offers several advantages, including reduced environmental pollution, minimized heat and humidity loss, and cost savings due to decreased anesthetic agent consumption. Desflurane has low blood solubility, allowing for rapid induction, early recovery and safe use in low-flow anesthesia. Objective: To compare emergence time, emergence quality, and anesthetic agent consumption between low-flow Desflurane and medium-flow Sevoflurane anesthesia in endoscopic sinus surgery. Methods: A randomized control study, single-blinded, in patients undergoing endoscopic sinus surgery. Results: The emergence time in the Desflurane group was shorter than in the Sevoflurane group (5.9 ± 1.1 minutes vs. 8.7 ± 1.4 minutes; p < 0.001). The time to orientation to name and place, and the time to achieve an Aldrete score ≥ 9 were also shorter in the Desflurane group (7.6 ± 1.3 minutes vs. 11 ± 1.6 minutes; p < 0.001 and 8.7 ± 1.3 minutes vs. 12.3 ± 1.4 minutes; p < 0.001, respectively). The prevalence of post-emergence agitation and airway irritation showed no significant difference between the two groups. The anesthetic agent consumption in the Desflurane group was higher than in the Sevoflurane group (46.6 ± 12.4 mL vs. 29.5 ± 10.5 mL; p < 0.001). Conclusion: Maintenance anesthesia with Desflurane in patients undergoing endoscopic sinus surgery shortened emergence time by 32.3% and provided better emergence quality compared to Sevoflurane.

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References

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