CORRELATION BETWEEN CORONARY ARTERY CALCIFICATION ON MULTIDETECTOR COMPUTED TOMOGRAPHY AND CORONARY ARTERY LESION SEVERITY ACCORDING TO SYNTAX SCORE ON ANGIOGRAPHY

Hà Nguyễn Công, Hùng Phạm Anh, Tuấn Nguyễn Quang

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Abstract

Introduction: Coronary artery disease (CAD) is a leading cause of mortality worldwide. Multidetector computed tomography (MSCT) allows for the assessment of coronary artery calcification (CAC) through the Agatston score, an indicator reflecting the degree of atherosclerosis. The SYNTAX score evaluates the complexity of CAD lesions and aids in determining treatment strategies. Objective: To explore the correlation between coronary artery calcification on MSCT and coronary artery lesion severity according to the SYNTAX score. Methods: A cross-sectional descriptive study was conducted on 111 patients at the Vietnam National Heart Institute. Patients underwent MSCT and coronary angiography. Data were analyzed using Stata 14.0 with appropriate statistical tests, ensuring compliance with ethical guidelines in biomedical research. Results: The Agatston score showed a strong correlation with the SYNTAX score in the overall study group (r = 0.53, p < 0.05) and the acute coronary syndrome group (r = 0.57, p < 0.05). However, no significant correlation was observed in the stable chest pain group (p > 0.05). The Agatston score was associated with lesion characteristics such as triple vessel disease, chronic total occlusion, long lesions, and diffuse lesions, but not with triple vessel narrowing or ostial lesions. Conclusion: Coronary artery calcification on MSCT is positively correlated with lesion severity according to the SYNTAX score. This correlation is significant in the acute coronary syndrome group but not in the stable chest pain group, possibly due to the small sample size.

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References

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