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Date Published: 28/04/2025
Abstract Views: 61
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DOI: https://doi.org/10.51298/vmj.v549i2.13805
Issue
Vol. 549 No. 2 (2025)
Section
Các bài báo
How to Cite
Trần Thị, H., & Phạm Thị Minh, P. (2025). SEROLOGICAL DIAGNOSIS OF CYTOMEGALOVIRUS IN PATIENTS WITH ERYTHEMA MULTIFORME, STEVENS-JOHNSON SYNDROME, AND TOXIC EPIDERMAL NECROLYSIS. Vietnam Medical Journal, 549(2). https://doi.org/10.51298/vmj.v549i2.13805

SEROLOGICAL DIAGNOSIS OF CYTOMEGALOVIRUS IN PATIENTS WITH ERYTHEMA MULTIFORME, STEVENS-JOHNSON SYNDROME, AND TOXIC EPIDERMAL NECROLYSIS

Huyền Trần Thị, Phương Phạm Thị Minh

Main Article Content

Abstract

A cross-sectional descriptive study was conducted on 54 patients with erythema multiforme (EM), 30 patients with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), and 30 healthy individuals to determine the seropositivity rates for cytomegalovirus (CMV) and its association with certain clinical features. The results showed that the rates of CMV-IgM and CMV-IgG positivity were 3.33% and 100% in the SJS/TEN group, 1.85% and 100% in the EM group, and 10% and 100% in the healthy group, respectively. The differences among the groups were not statistically significant. Within the EM group, there were no differences in CMV-IgM and CMV-IgG positivity rates between patients with diffuse skin lesions and those with acral, localized lesions, nor between patients with mucosal involvement and those without mucosal involvement. Similarly, in the SJS/TEN and EM groups, there were no differences in CMV-IgM and CMV-IgG seropositivity rates between patients with unknown causes and those with suspected drug-induced disease.

Article Details

Keywords

Cytomegalovirus, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

References

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