APPLICATION RIDA ALLERGY SCREEN TO DETERMINE MULTI - E GLOBULIN IMMUNE DISTRIBUTION PATTERNS USING QUANTITATIVE SPECIAL IN SERUM VIETNAMESE PEOPLE

Tóm tắt

Introduction: RIDA qLine® Allergen Serum is individual diagnostic and treatment confirmatory test in patients with unknown etiology or multiple allergens. Research to find distribution patterns of multi- allergens in the population. Methods: Retrospective analysis 538 samples from 2022 to 2024 in adults (Table 1 Viet) and children (Table 4) at Medic Medical Center, HCMc. Automated s-IgE quantification using nitrocellulose membrane immunoblot method to explore the relationship between s-IgE and ten common inhalant allergens based on a maximum value of 6.0 and a minimum value of 1.0 with a reference range < 0.35 IU/mL similar to normal RAST < 1. Results: sIgE was positive with a rate of 44.6% (mean 2.96±1.49) Dermatophagoides pteronyssinus (Dp), 51.1% (mean 2.55±1.39) Dermatophagoides farina (Df), 50% (mean 2.73±1.38) Blomia tropicalis (Bt), 3.1% cat hair (mean 2.69±1.28), 3.5% dog hair (mean 2.13±1.41), 0% mouse hair, 10.9% cockroach (mean 1.85±0.77), 9.2% feathers mixture (mean 1.73 ±0.68), 15.5% grass mixture (mean 1.55±0.69). The population is divided into 3 groups: (A) 39.5% negative non-allergic, (B) positive sensitive 38.6% dominant house dust mite and (C) 28.4% positive for systemic. Samples are often positive simultaneously Dp, Df, Bt and good correlations r=0.8 between Dp and Df, r=0.7 between Dp and Bt, r=0.9 between Df and Bt. Conclusions: In most patients with multiple allergens, the incidence of low concentrations predominates and decreases at medium and high concentrations. House dust mites spp, mainly Dp, Df, Bt are one of the common complex respiratory allergens and have strong correlation.