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Date Published: 05/05/2025
Abstract Views: 78
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DOI: https://doi.org/10.51298/vmj.v549i3.13946
Issue
Vol. 549 No. 3 (2025)
Section
Các bài báo
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Trần Hoàng, C., & Đào Đức, T. (2025). CLINICAL AND SUB-CLINICAL CHARACTERISTICS OF GASTROINTESTINAL STROMAL TUMORS (GISTs) AT MILITARY HOSPITAL 175. Vietnam Medical Journal, 549(3). https://doi.org/10.51298/vmj.v549i3.13946

CLINICAL AND SUB-CLINICAL CHARACTERISTICS OF GASTROINTESTINAL STROMAL TUMORS (GISTs) AT MILITARY HOSPITAL 175

Cường Trần Hoàng, Tiến Đào Đức

Main Article Content

Abstract

Objective: Describing the clinical and paraclinical characteristics and the relationship between pathology and disease characteristics patients diagnosed with gastrointestinal stromal tumors (Gastrointestinal Stromal Tumors - GISTs) treated at the Military Hospital. 175. Subjects and methods: Retrospective cross-sectional study on 31 patients diagnosed with gastrointestinal stromal tumor treated at Military Hospital 175 from January 2022 to September 2024. Results: 61,3% of patients were men; The average age is 53,9 years old. 74,2% of patients had symptoms of abdominal pain. 48,5% of patients were detected through abdominal computed tomography. 45,2% of patients presented with stomach disease. Chi square test between mitotic index, histological characteristics and metastatic status showed p = 0.379 and p = 0.371, respectively. Conclusion: Gastrointestinal stromal tumors are common in men, aged between 40-60, and the most common location is the stomach. There is no relationship between mitotic index, histological grade and metastatic status.

Article Details

Keywords

Gastrointestinal stromal tumor, GISTs

References

1. Đỗ Hùng Kiên (2017). Nghiên cứu kết quả điều trị u mô đệm đường tiêu hoá (GISTs) giai đoạn muộn bằng Imatinib tại Bệnh viện K. Luận văn Tiến sỹ Y học, Đại học Y Hà Nội.
2. Akahoshi K, Oya M, Koga T, Shiratsuchi Y (2018) Current clinical management of gastrointestinal stromal tumor. World J Gastroenterol. 2018 Jul 14;24(26):2806-2817. doi: 10.3748/wjg.v24.i26.2806. PMID: 30018476; PMCID: PMC6048423.
3. Nguyễn, T. P., Nguyễn, T. Đức, & Dương, T. L. (2024). Đánh giá kết quả điều trị imatinib trên bệnh nhân u mô đệm đường tiêu hóa (GISTs) tại bệnh viện K. Tạp Chí Y học Việt Nam, 538(3). https://doi.org/10.51298/vmj.v538i3.9567
4. Gia Anh, P., & Hồng Sơn, T.(2021). Đặc điểm lâm sàng ung thư ống tiêu hóa không thuộc biểu mô được phẫu thuật tại bệnh viện hữu nghị Việt Đức trong 10 năm. Tạp Chí Y học Việt Nam, 498(2). https://doi.org/10.51298/vmj. v498i2.194
5. Jumniensuk C, Charoenpitakchai M. (2018) Gastrointestinal stromal tumor: clinicopathological characteristics and pathologic prognostic analysis. World J Surg Oncol. 2018 Dec 3;16(1):231. doi: 10.1186/s12957-018-1532-1. PMID: 30509310; PMCID: PMC6277996.
6. Nguyen Cuong P, Thanh Xuan N, Xuan Tien T, Nhu Huy P, Nguyen Tuong P (2020). Histopathological Characteristics of Gastrointestinal Stromal Tumors in a Cohort of Vietnamese Patients. Clin Pathol. 2020 Nov 11;13:2632010X20972405. doi: 10.1177/ 2632010X20972405. PMID: 33241209; PMCID: PMC7672773.
7. IJzerman NS, van Werkhoven E, Mohammadi M, Hollander DD, Bleckman RF, Reyners AKL, Desar IME, Gelderblom H, Grünhagen DJ, Mathijssen RHJ, Steeghs N, van der Graaf WTA (2020). Sex differences in patients with gastrointestinal stromal tumours: do they exist and does it affect survival? ESMO Open. Dec;7(6):100649. doi: 10.1016/j.esmoop. 2022.100649. Epub 2022 Dec 6. PMID: 36493601; PMCID: PMC9808455.
8. Rong J, Chen S, Song C, Wang H, Zhao Q, Zhao R, He Y, Yan L, Song Y, Wang F, Xie Y (2020). The prognostic value of gender in gastric gastrointestinal stromal tumors: a propensity score matching analysis. Biol Sex Differ.Jul 23;11(1):43. doi: 10.1186/s13293-020-00321-8. PMID: 32703269; PMCID: PMC7376864.