MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TIÊN LƯỢNG SỐC NHIỄM KHUẨN VÀ TỬ VONG Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG MẮC NHIỄM KHUẨN HUYẾT

Abstract

Retrospective study of 176 patients diagnosed diabetes with septicemia, hospitalized at the National Hospital for Tropical Diseases from 2016 to 2021 to investigate factors associated  with septic shock and mortality in these patients. Septicemia was confirmed by clinical cricteria and positive blood culture. Results: The rate of septic shock in the study was 17.06%, the mortality rate was 9.1%. There was no difference in blood glucose and HbA1c levels at admission between patients with septic shock and without septic shock, between survivors and non-survivors, and between gram-positive septicememia and gram-negative septicemia. Multivariate logistic regression analysis showed that Glasgow score <15 (OR = 4.876; 95%CI: 1.635-14.545; p=0.04) and CRP levels at admission (OR=1.005; 95%CI 1.001-1.009, p=0.018) were independent prognostic factors for septic shock. Septic shock is an independent prognostic factor for mortality in diabetic patients with septicemia (OR = 33.355; 95%CI: 4.124-269.743; p=0.001). Conclusion: In diabetic patients with septicemia, there was no association between blood glucose and HbA1c levels at admission with septic shock and mortality. Independent prognostic factors for septic shock were impaired consciousness and CRP levels at admission. Independent prognostic factor for mortality was septic shock.