ĐẶC ĐIỂM CỦA TỔN THƯƠNG MÓNG TRONG BỆNH VẢY NẾN

Abstract

This cross-sectional study aimed to investigate the clinical characteristics of nail lesions in patients with psoriasis, was conducted on 169 psoriasis patients presenting with nail involvement at the National Hospital of Dermatology and Venereology between August 2020 and August 2021. The severity of skin lesions was evaluated using the Psoriasis Area and Severity Index (PASI), while nail involvement was quantified using both the Nail Psoriasis Severity Index (NAPSI) and the Nijmegen Nail Psoriasis Activity Index (N-NAIL). The results showed that the average number of affected nails were 7.5. The most frequently observed nail matrix abnormalities were pitting (84.6%), transverse grooves (37.3%), nail crumbling (55.0%), and leukonychia (47.9%), whereas nail bed abnormalities included oil-drop signs (65.7%), onycholysis (38.5%), subungual hyperkeratosis (73.4%), and Splinter hemorrhages (20.7%). The mean NAPSI score was 36.7 ± 13.2 (range 10-78); the mean N-NAIL score was 59.8 ± 21.8 (range 20-130). Furthermore, significant positive correlations were observed between PASI and NAPSI (r = 0.547, p < 0.001); PASI and N-NAIL (r = 0.562, p < 0.001); NAPSI and N-NAIL (r = 0.965, p < 0.001). The majority of patients reported that nail lesions affected aesthetics (133 patients; 78.7%); pain (42 patients; 24.9%); mobility (53 patients; 31.4%).