GIÁ TRỊ CỦA CẮT LỚP VI TÍNH ĐỊNH LƯỢNG TRONG CHẨN ĐOÁN KHÍ PHẾ THŨNG Ở NGƯỜI BỆNH PHỔI TẮC NGHẼN MẠN TÍNH

Abstract

High-resolution computed tomography (HRCT) of the lungs plays a crucial role in quantifying emphysematous lung regions caused by airway narrowing and alveolar surface damage. Emphysematous lung areas are defined as regions with low attenuation (< -950 HU), and the percentage of low-attenuation areas (LAA%) can be calculated. This cross-sectional descriptive study included 59 patients with chronic obstructive pulmonary disease (COPD) diagnosed and treated at Hanoi Medical University Hospital from July 2024 to January 2025. Patients underwent pulmonary function testing (FEV1) and high-resolution computed tomography (HRCT) of the lungs. The LAA% was automatically measured using Ziostation software by Ziosoft. The severity of COPD was classified based on the LAA% (GODDARD scoring system) and FEV1 values (GOLD classification).The study results demonstrated a moderate correlation between the GODDARD score (classification based on LAA%) and the GOLD classification (based on pulmonary function FEV1), with r = 0.35, which was statistically significant (p = 0.007). These findings suggest that LAA% is a useful parameter for assessing pulmonary emphysema on HRCT imaging and can also serve as an indirect estimate of pulmonary function.