ĐẶC ĐIỂM CỦA NGƯỜI BỆNH VIÊM GAN VI RÚT C MẠN TÍNH TRƯỚC ĐIỀU TRỊ BẰNG PHÁC ĐỒ DAAS TẠI 02 BỆNH VIỆN BỆNH NHIỆT ĐỚI

Abstract

Objective: To describe the clinical and demographic characteristics of patients with chronic hepatitis C treated with DAAs at the National Hospital for Tropical Diseases (NHTD) and the Ho Chi Minh City Hospital for Tropical Diseases (HTD). Methods: This is a randomized controlled clinical trial. Patients will be randomly assigned to two groups at a ratio of 1:1. Results: The study included 250 patients, of which the study group at the HTD and NHTD accounted for 23.2% and 26.4% of the total study subjects, respectively. The control group at the HTD and NHTD accounted for 23.6% and 26.8% of the total study subjects, respectively. The study subjects had many underlying diseases such as depression, cancer, peripheral neuropathy, angina, and COPD. Notably, patients in this study also had tuberculosis accounting for 4%, hyperlipidemia accounting for 4%, diabetes accounting for 7.5% and hypertension accounting for 11.1%. All patients participating in the study had a hemoglobin level ≧ 12 g/dl, 4.8% of patients still had platelet levels between 100-150G/l and 4.4% of patients had white blood cells below 4.5G/l. The group of patients at the HTD had a viral load ≥4 x105 UI/ml accounting for 60.7%, while this index in patients treated at the NHTD was 80.5%. Conclusion: Patients with chronic hepatitis C participating in the study were evenly distributed in the 2 hospitals and still had many underlying diseases, high viral load before treatment. Hemoglobin, platelet and white blood cell indices were still normal.