U MÀNG NÃO BIỂU HIỆN Ở PHỔI - MỘT TRƯỜNG HỢP HIẾM GẶP

Abstract

This report presents a case of primary pulmonary meningioma (PPM) that was successfully diagnosed and treated. Case report: A 57-year-old female patient was admitted with persistent chest pain. Contrast-enhanced computed tomography (CT) of the chest revealed a well-circumscribed 1.5 cm mass in segment 10 of the right lung without evidence of invasion or distant metastasis. The patient underwent video-assisted thoracoscopic surgery for segmentectomy. Results: Postoperative histopathological examination confirmed a tumor composed of spindle/oval cells arranged in whorled patterns with a fibrous stroma. Immunohistochemistry showed EMA (+), PR (+), CKAE1/AE3 (+), low Ki67, while markers for lung cancer (S-100, P40, TTF-1, STAT6, CD34, GFAP) were negative. These findings confirmed the diagnosis of Grade 1 primary pulmonary meningioma (PPM), meningothelial subtype. The patient recovered well postoperatively with no major complications.This case underscores the significance of recognizing PPM as a rare but treatable condition when detected early. Surgical resection remains the mainstay of treatment with excellent prognosis, but long-term follow-up is necessary to monitor for recurrence.