NGHIÊN CỨU KẾT CỤC THAI KỲ VÀ CÁC YẾU TỐ LIÊN QUAN NHAU BONG NON Ở THAI KỲ 28 ĐẾN 41 TUẦN TẠI BỆNH VIỆN TỪ DŨ

Abstract

Background: Abruptio placentae (AP) refers to the premature separation of the placenta from the uterine wall, either partially or completely, before the delivery of the fetus. This condition results in the formation of a retroplacental hematoma, which progressively enlarges, further separating the placenta and fetal membranes from the uterine wall, thereby disrupting the maternal-fetal circulation. Abruptio placentae is a sudden-onset condition with rapid progression from mild to severe, posing significant risks to both the mother and fetus. Objective: To identify factors associated with abruptio placentae and to evaluate pregnancy outcomes in women with gestational age from 28 to 41 weeks diagnosed with abruptio placentae at Tu Du Hospital. Methods: A case-control study was conducted. Pregnant women with gestational age between 28 and 41 weeks who underwent cesarean section at Tu Du Hospital from January 2022 to October 2023 were divided into two groups: case group and control group. Results: Preeclampsia significantly increased the risk of abruptio placentae (p < 0.05), with severe preeclampsia elevating the risk by 3.4 times. Abruptio placentae increased the risk of uterine artery ligation by 4.02 times (95% CI: 1.52 - 10.6), which was statistically significant (p < 0.05), compared to women without abruptio placentae. Additionally, the risk of neonatal infection was 2.48 times higher in cases with abruptio placentae, also reaching statistical significance (p < 0.05). Conclusion: In pregnant women at high risk of preeclampsia, preventive strategies should be implemented along with vigilant monitoring for signs of abruptio placentae. For patients already diagnosed with preeclampsia, particularly those with severe preeclampsia, close observation is essential to ensure early detection and timely intervention of abruptio placentae for the benefit of both mother and fetus.