A STUDY ON PREGNANCY OUTCOMES AND ASSOCIATED FACTORS OF ABRUPTIO PLACENTAE IN PREGNANCIES FROM 28 TO 41 WEEKS AT TU DU HOSPITAL
Main Article Content
Abstract
Background: Abruptio placentae (AP) refers to the premature separation of the placenta from the uterine wall, either partially or completely, before the delivery of the fetus. This condition results in the formation of a retroplacental hematoma, which progressively enlarges, further separating the placenta and fetal membranes from the uterine wall, thereby disrupting the maternal-fetal circulation. Abruptio placentae is a sudden-onset condition with rapid progression from mild to severe, posing significant risks to both the mother and fetus. Objective: To identify factors associated with abruptio placentae and to evaluate pregnancy outcomes in women with gestational age from 28 to 41 weeks diagnosed with abruptio placentae at Tu Du Hospital. Methods: A case-control study was conducted. Pregnant women with gestational age between 28 and 41 weeks who underwent cesarean section at Tu Du Hospital from January 2022 to October 2023 were divided into two groups: case group and control group. Results: Preeclampsia significantly increased the risk of abruptio placentae (p < 0.05), with severe preeclampsia elevating the risk by 3.4 times. Abruptio placentae increased the risk of uterine artery ligation by 4.02 times (95% CI: 1.52 - 10.6), which was statistically significant (p < 0.05), compared to women without abruptio placentae. Additionally, the risk of neonatal infection was 2.48 times higher in cases with abruptio placentae, also reaching statistical significance (p < 0.05). Conclusion: In pregnant women at high risk of preeclampsia, preventive strategies should be implemented along with vigilant monitoring for signs of abruptio placentae. For patients already diagnosed with preeclampsia, particularly those with severe preeclampsia, close observation is essential to ensure early detection and timely intervention of abruptio placentae for the benefit of both mother and fetus.
Article Details
Keywords
Abruptio placentae, preeclampsia, severe preeclampsia
References

2. Nguyễn Thị Thanh Hà. Xuất huyết ba tháng cuối thai kỳ: Nhà xuất bản y học. 2014. 139-47 p.

3. Jennifer M. Hill SY, Haylea S. Patrick, et al,. Pregnancy complications among women diagnosed with placenta previa and placental abruption. American Journal of Obstetrics & Gynecology. 2020;222(1):S292-S3.

4. Lê Hoàng, Đặng Thị Minh Nguyệt. Mô tả đặc điểm lâm sàng rau bong non. Tạp chí Phụ sản. 2015;13(3):86-9. doi: 10.46755/vjog.2015.3.900.


5. Ananth CV, Lavery JA, Vintzileos AM, Skupski DW, Varner M, Saade G, et al. Severe placental abruption: clinical definition and associations with maternal complications. Am J Obstet Gynecol. 2016;214(2):272 e1- e9. doi: 10.1016/j.ajog.2015.09.069.


6. Naruse K, Shigemi D, Hashiguchi M, Imamura M, Yasunaga H, Arai T, et al. Placental abruption in each hypertensive disorders of pregnancy phenotype: a retrospective cohort study using a national inpatient database in Japan. Hypertens Res. 2021;44(2):232-8. doi: 10.1038/s41440-020-00537-6.


7. Đinh Văn Hoàng, Trần Thi Len. Đặc điểm lâm sàng và cận lâm sàng của rau bong non tại bệnh viện phụ sản thái bình Tạp chí y dược Thái Bình. 2023;08:83-8.

8. Kiều Tiến Quyết. Nghiên cứu chẩn đoán và xử trí rau bong non tại bệnh viện phụ sản Hà nội. Luận văn thạc sỹ y học, Đại học Y Hà Nội. 2015.

9. Macheku GS, Philemon RN, Oneko O, Mlay PS, Masenga G, Obure J, et al. Frequency, risk factors and feto-maternal outcomes of abruptio placentae in Northern Tanzania: a registry-based retrospective cohort study. BMC pregnancy and childbirth. 2015;15(1):242. doi: 10.1186/s12884-015-0678-x.


10. Toivonen S, Heinonen S, Anttila M, Kosma VM, Saarikoski S. Reproductive risk factors, Doppler findings, and outcome of affected births in placental abruption: a population-based analysis. Am J Perinatol. 2002;19(8):451-60. doi: 10.1055/s-2002-36868.

