TÌNH TRẠNG MỆT MỎI MẠN TÍNH VÀ CÁC YẾU TỐ NGUY CƠ Ở BỆNH NHÂN VIÊM KHỚP DẠNG THẤP

Abstract

Objectives: 1. To evaluate the characteristics of chronic fatigue in patients with rheumatoid arthritis. 2. To determine the risk factors of chronic fatigue in these patients. Subjects and method: A cross-sectional descriptive study, including 60 patients diagnosed with rheumatoid arthritis according to ACR-EULAR 2010 criteria at the Musculoskeletal Center - Bach Mai Hospital from August 2024 to March 2025. Results: Chronic fatigue syndrome was found in 78.3% of patients with rheumatoid arthritis. The patients had an average BRAF-MDQ score of 27.82 ± 18.97, of which the most affected were the physical fatigue score of 11.43 ± 7.11 and the cognitive fatigue score of 7.92 ± 5.89. Factors that increased the risk of chronic fatigue symptoms in rheumatoid arthritis patients included: high disease activity, multiple deformed joints due to disease progression leaving joint adhesions and the disease was not well controlled with conventional DMARDs and biological DMARDs. Conclusions: Chronic fatigue syndrome was a very common extra-articular manifestation in patients with rheumatoid arthritis, especially during disease progression and greatly affects the patient's quality of life. Good control of disease progression with a targeted treatment regimen including conventional DMARDs and biological DMARDs will help improve the prognosis and reduce the risk of disability for these patients.