CT IMAGING AND THE DIAGNOSIS OF T3 INVASION IN UPPER TRACT UROTHELIAL CARCINOMA: THE VALUE OF PREOPERATIVE RADIOLOGICAL ASSESSMENT
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Abstract
Background: Pathological stage T3 invasion is a key prognostic factor in upper tract urothelial carcinoma (UTUC). Identifying preoperative CT imaging features associated with T3 invasion can aid in surgical planning and risk stratification. Methods: A retrospective descriptive study was conducted on patients with UTUC who underwent surgery at Binh Dan Hospital between January 2020 and June 2022. All patients had preoperative contrast-enhanced multiphasic CT scans and postoperative histopathological results. CT findings including irregular wall thickening, perirenal/periureteral fat stranding or obliteration, adjacent soft tissue invasion, and enhancing tumor mass were analyzed for their association with pathological T3 invasion. Results: A substantial proportion of patients showed pathological T3 invasion. CT features significantly associated with T3 stage included obliteration of perirenal/periureteral fat planes and adjacent soft tissue extension (p < 0.01). These findings demonstrated high sensitivity and positive predictive value in detecting T3 disease. Conclusion: Several CT features are strongly associated with pathological T3 invasion in UTUC. Recognizing these radiologic signs can support preoperative staging and optimize clinical decision-making.
Article Details
Keywords
Computed tomography, upper tract urothelial carcinoma, T3 invasion, imaging features, preoperative assessment
References
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