CT IMAGING AND THE DIAGNOSIS OF T3 INVASION IN UPPER TRACT UROTHELIAL CARCINOMA: THE VALUE OF PREOPERATIVE RADIOLOGICAL ASSESSMENT

Toàn Đỗ Anh, Đức Võ Tấn, Phong Nguyễn Chí, Thủy Nguyễn Thị Thanh

Main Article Content

Abstract

Background: Pathological stage T3 invasion is a key prognostic factor in upper tract urothelial carcinoma (UTUC). Identifying preoperative CT imaging features associated with T3 invasion can aid in surgical planning and risk stratification. Methods: A retrospective descriptive study was conducted on patients with UTUC who underwent surgery at Binh Dan Hospital between January 2020 and June 2022. All patients had preoperative contrast-enhanced multiphasic CT scans and postoperative histopathological results. CT findings including irregular wall thickening, perirenal/periureteral fat stranding or obliteration, adjacent soft tissue invasion, and enhancing tumor mass were analyzed for their association with pathological T3 invasion. Results: A substantial proportion of patients showed pathological T3 invasion. CT features significantly associated with T3 stage included obliteration of perirenal/periureteral fat planes and adjacent soft tissue extension (p < 0.01). These findings demonstrated high sensitivity and positive predictive value in detecting T3 disease. Conclusion: Several CT features are strongly associated with pathological T3 invasion in UTUC. Recognizing these radiologic signs can support preoperative staging and optimize clinical decision-making. 

Article Details

References

1. Rouprêt M, Babjuk M, Compérat E, et al. EAU Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update. Eur Urol. 2023;83(1):1-15. doi:10.1016/j.eururo.2022.09.011
2. Brierley JD, Gospodarowicz MK, Wittekind C. TNM Classification of Malignant Tumours. 8th ed. Wiley-Blackwell; 2017.
3. Janisch F, Shariat SF, Baltzer P, et al. Diagnostic accuracy of multidetector computed tomography for upper tract urothelial carcinoma: systematic review and meta-analysis. World J Urol. 2020;38(5):1165–1175. doi:10.1007/s00345 -019-02875-8