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EVALUATION OF THE EFFECTIVENESS OF FRACTIONAL CO₂ LASER COMBINED WITH TOPICAL HYALURONIC ACID IN THE TREATMENT OF ATROPHIC ACNE SCARS AT THE DEPARTMENT OF DERMATOLOGY AND SKIN AESTHETICS, UNIVERSITY MEDICAL CENTER HO CHI MINH CITY
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Abstract
Objectives: Evaluation of the effectiveness of fractional CO₂ laser combined with topical hyaluronic acid (HA) in patients with atrophic acne scars. Subjects and Methods: A descriptive case series with longitudinal data analysis, on 22 patients with atrophic acne scars who presented to the Department of Dermatology – Aesthetic Dermatology, University Medical Center Ho Chi Minh City, from January 2025 to June 2025. Results: The échelle d'évaluation clinique des cicatrices d'acné (ECCA) grading scale showed a statistically significant reduction at week 8 (98.6 ± 27.9) compared to baseline (118.6 ± 31.0). The texture index also demonstrated a statistically significant improvement at week 8, with a median value of 80.5% [73.8%; 87.8%], compared to a baseline median of 78.0% [73.0%; 84.0%]. All three scar types (ice-pick, boxcar, and rolling) exhibited statistically significant improvements at both week 4 and week 8. At week 8, boxcar scars showed the greatest improvement, with a median of 62.5% [50.0%; 88.9%], followed by ice-pick scars at 40.2% [23.4%; 51.0%], while rolling scars demonstrated the least improvement, with a median of 35.4% [11.4%; 59.2%]. Conclusion: The combined treatment of fractional CO₂ laser and topical HA demonstrated improvement in atrophic acne scars, as assessed by the ECCA score and skin texture index after 8 weeks. This approach was effective for all three scar types.
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Keywords
Atrophic acne scars, fractional CO₂ laser, hyaluronic acid
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