CLINICAL AND PARACLINICAL FEATURES OF BILATERAL THYROID CANCER UNDERGOING TRANSORAL ENDOSCOPIC THYROIDECTOMY

Hậu Nguyễn Xuân, Hiền Nguyễn Xuân, Trí Ngô Minh, Quảng Lê Văn

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Abstract

Objective: To evaluate the clinical and paraclinical characteristics of patients with bilateral thyroid cancer undergoing transoral endoscopic thyroidectomy vestibular approach (TOETVA) at Hanoi Medical University Hospital. Subjects and Methods: A prospective study was conducted on 30 eligible patients who underwent TOETVA at the Oncology Center, Hanoi Medical University Hospital, from January 2020 to July 2024. Clinical, paraclinical, and surgical characteristics were recorded. Results: A total of 29 female patients and 1 male patient were included in the study. The mean age was 33.1 ± 8.6 years (range: 16–51 years). The mean number of nodules was 1.76 ± 1.15 in the left thyroid lobe, 1.71 ± 0.99 in the right lobe, and 3.75 ± 1.39 for both lobes combined. Multifocality was observed in 14 patients (46.7%) in the left lobe, 17 patients (56.7%) in the right lobe, and 8 patients (26.7%) in both lobes. The mean size of the largest tumor in each lobe was 6.56 ± 5.11 mm in the left lobe and 5.78 ± 3.91 mm in the right lobe. All patients underwent total thyroidectomy with prophylactic bilateral central neck dissection. Postoperative histopathological examination confirmed the diagnosis of papillary thyroid carcinoma in all patients (100%). Central neck lymph node metastasis was detected in 14 patients (46.7%). Extrathyroidal extension was detected in 7 patients (23.3%). Conclusion: Bilateral thyroid cancer had high prevalence of multifocality, cervical lymph node metastasis, and extrathyroidal extension.

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References

1. Cancer Today. Accessed April 13, 2024. https://gco.iarc.who.int/today/
2. Ohgami M, Ishii S, Arisawa Y, et al. Scarless endoscopic thyroidectomy: breast approach for better cosmesis. Surg Laparosc Endosc Percutan Tech. 2000;10(1):1-4.
3. Joseph KR, Edirimanne S, Eslick GD. Multifocality as a prognostic factor in thyroid cancer: A meta-analysis. International Journal of Surgery. 2018;50: 121-125. doi:10.1016/j.ijsu. 2017.12.035
4. Xuan HN, Anh TD, Xuan HN, Thai DP, Le Van Q. Occult Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma Patients Undergoing TOETVA Procedure. J Thyroid Res. 2023;2023:4779409. doi:10.1155/2023/4779409
5. Nguyen HX, Nguyen HX, Nguyen HV, Nguyen LT, Nguyen TTP, Le QV. Transoral Endoscopic Thyroidectomy by Vestibular Approach with Central Lymph Node Dissection for Thyroid Microcarcinoma. J Laparoendosc Adv Surg Tech A. 2021;31(4): 410-415. doi:10.1089/lap.2020. 0411
6. Is the Multifocality Rate in Thyroid Cancer Patients Increasing Over the Years | Request PDF. ResearchGate. Published online October 22, 2024. doi:10.5505/ejm.2023.18853
7. Nguyen XH, Nguyen XH, Nguyen TL, Pham TD, Le VQ. Transoral Endoscopic Thyroidectomy by Vestibular Approach for Differentiated Thyroid Cancer Intraoperatively Invading Strap Muscle. Surg Laparosc Endosc Percutan Tech. 2021; 32(2): 172-175. doi:10.1097/SLE. 0000000000001020
8. Ahn J hyuk, Yi JW. Transoral endoscopic thyroidectomy for thyroid carcinoma: outcomes and surgical completeness in 150 single-surgeon cases. Surg Endosc. 2020;34(2):861-867. doi:10.1007/s00464-019-06841-8
9. Nguyen HX, Nguyen HX, Nguyen TTP, Van Le Q. Transoral endoscopic thyroidectomy by vestibular approach in Viet Nam: surgical outcomes and long-term follow-up. Surg Endosc. 2022;36(6):4248-4254. doi:10.1007/s00464-021-08759-6