CLINICAL AND PARACLINICAL CHARACTERISTICS OF PEDIATRIC THYROID CANCER PATIENTS UNDERGOING TRANSORAL ENDOSCOPIC SURGERY AT HANOI MEDICAL UNIVERSITY HOSPITAL
Main Article Content
Abstract
Objective: To describe the clinical and paraclinical characteristics of pediatric thyroid cancer patients undergoing transoral endoscopic thyroidectomy (TOETVA) at Hanoi University of Medicine Hospital. Method: A cross-sectional study was conducted on 15 patients at the Oncology Center, Hanoi University of Medicine Hospital from February 2020 to September 2024. Results: The average age in the study group was 16.2±2.1 (11-18) years, with 13 female patients (86.7%) and 2 male patients (13.3%). Twelve patients (80%) underwent thyroid lobectomy with central neck dissection on the same side, and 3 patients (20%) had total thyroidectomy with bilateral central neck dissection. The average number of lymph nodes retrieved and the number of metastatic nodes were 8.3±5.4 and 2.9±3.5, respectively, with an occult lymph node metastasis rate of 53.3%. The average tumor size in the study group and the metastatic node group were 11.7±6.2 mm and 13±6.2 mm, respectively. Two patients (13.3%) had multifocal thyroid cancer. Postoperative histopathology showed that 14 patients (93.3%) had conventional papillary thyroid carcinoma, 1 patient (6.7%) had diffuse sclerosing variant papillary thyroid carcinoma, and 20% had concomitant thyroiditis. Conclusion: Pediatric thyroid cancer treated with transoral endoscopic thyroidectomy is commonly detected in older children, with characteristics such as large tumor size, multifocality, and a high rate of occult lymph node metastasis.
Article Details
Keywords
TOETVA, pediatric thyroid cancer
References
2. Zimmerman D, Hay ID, Gough IR, et al. Papillary thyroid carcinoma in children and adults: long-term follow-up of 1039 patients conservatively treated at one institution during three decades. Surgery. 1988;104(6):1157-1166.
3. Nhận xét một số đặc điểm lâm sàng và cận lâm sàng ung thư tuyến giáp thể biệt hoá ở trẻ em. Accessed March 24, 2025. https://tapchiyhocvietnam.vn/index.php/vmj/article/view/5325/4842
4. Kết quả sớm phẫu thuật nội soi đường miệng điều trị ung thư tuyến giáp thể biệt hóa ở nam giới. Accessed March 24, 2025. https://tapchiyhocvietnam.vn/index.php/vmj/article/view/9790/8629
5. Kết quả phẫu thuật ung thư tuyến giáp thể biệt hóa ở nam giới. Accessed March 24, 2025. https://tapchinghiencuuyhoc.vn/index.php/tcncyh/article/view/85/61
6. Kết quả sớm phẫu thuật nội soi đường miệng điều trị ung thư tuyến giáp thể nhú cT1aN0M0 tại Bệnh viện Đại học Y Hà Nội. Accessed March 24, 2025. https://tapchi nghiencuuyhoc.vn/index.php/tcncyh/article/view/2031/1326
7. Sudoko CK, Jenks CM, Bauer AJ, et al. Thyroid Lobectomy for T1 Papillary Thyroid Carcinoma in Pediatric Patients. JAMA Otolaryngol Head Neck Surg. 2021;147(11):943-950. doi:10.1001/jamaoto.2021.2359
8. Memeh K, Ruhle B, Alsafran S, et al. Total Thyroidectomy vs Thyroid Lobectomy for Localized Papillary Thyroid Cancer in Children: A Propensity-Matched Survival Analysis. Journal of the American College of Surgeons. 2021; 233 (1):39-49. doi:10.1016/j.jamcollsurg.2021. 03.025
9. Cherella CE, Richman DM, Liu E, et al. Predictors of Bilateral Disease in Pediatric Differentiated Thyroid Cancer. J Clin Endocrinol Metab. 2021;106(10):e4242-e4250. doi:10.1210/ clinem/dgab210
10. Keefe G, Culbreath K, Cherella CE, et al. Autoimmune Thyroiditis and Risk of Malignancy in Children with Thyroid Nodules. Thyroid. 2022; 32(9): 1109-1117. doi:10.1089/thy.2022. 0241