CHARACTERISTICS OF CHILDREN'S TUBERCULOSIS TREATED AT THE PEDIATRIC DEPARTMENT - NATIONAL LUNG HOSPITAL
Main Article Content
Abstract
Objective: To describe the characteristics of the pediatric tuberculosis model treated at the Pediatrics Department - National Lung Hospital in 2017 and 2018. Research methodology: A cross-sectional descriptive study. Results: The study included 407 pediatric patients, the most common age group was under 5 years old (45.5%) and 36.1% of the patient had a history of exposure to sources of pulmonary tuberculosis; the time to detect the disease was usually 2-4 weeks (31.5%). In pediatric tuberculosis, pulmonary tuberculosis accounted for the majority (65.6%) and the rate of diagnosis with bacterial evidence accounted for 37.8% (pulmonary tuberculosis was 42.7% and extrapulmonary tuberculosis was 28.6%). Childhood tuberculosis was mainly the tuberculosis of one organ (72.7%) (of which pulmonary tuberculosis accounted for 55.1%); The tuberculosis in two organs accounted for 23.1%; tuberculosis in three organs was 3.9% and there was 01 child with tuberculosis in 04 organs. For pulmonary tuberculosis, bacterial evidence was detected from gastric fluid specimens accounted for 20.6%, followed by sputum specimens (8.6%). For children's pulmonary tuberculosis in both groups of with and without bacterial evidence, the pair of clinical symptom and diagnostic imaging was most common (63.7%). And for extrapulmonary tuberculosis, the most common pair was clinical symptom and subclinical (84.3%). These pairs of factors were valuable in clinical practice in making decisions to diagnose children's tuberculosis when no bacterial evidence was found.
Article Details
Keywords
Children's tuberculosis, pulmonary tuberculosis, extrapulmonary tuberculosis
References


2. Moon TD, Nacarapa E, Verdu ME, et al. Tuberculosis Treatment Outcomes Among Children in Rural Southern Mozambique: A 12-year Retrospective Study. Pediatr Infect Dis J. 2019;38(10): 999-1004. doi:10.1097/ inf.0000000000002435. Published October, 2019. Accessed June 22, 2022.


3. Hoàng Thanh Vân. Nghiên cứu đặc điểm lâm sàng, cận lâm sàng lao phổi trẻ em và tính kháng thuốc của vi khuẩn. Luận án tiến sĩ y học. 2011. Trường Đại học Y Hà Nội.

4. Silva JB, Santos JC, Barbosa L, Carvalho I. Tuberculosis in the paediatric age group: a reflection on transmission. An Pediatr (Engl Ed). 2021;94(6): 403-411. doi:10.1016/j.anpede. 2020.12.002. Published December 25, 2020. Accessed August 22, 2022.


5. Alavi SM, Salmanzadeh S, Bakhtiyariniya P, et al. Prevalene and treatment outcome of pulmonary and extrapulmonary pediatric tuberculosis in southwestern Iran. Caspian J Interm Med. 2015;6(5):213-219. https://pubmed. ncbi.nlm.nih.gov/ 26644895/. Published September 1, 2015. Accessed June 22, 2022.

6. WHO. WHO consolidated guidelines on tuberculosis: Module 5: Management of tuberculosis in children and adolescents. 2022. WHO Guidelines Approved by the Guidelines Review Committee. https://www.who.int/ publications/i/item/9789240046764. Published March 18, 2022. Accessed February 22, 2023.

7. Chương trình chống lao quốc gia. Hướng dẫn chẩn đoán, điều trị và dự phòng bệnh lao. 2024.

8. Marais BJ, Gie RP, Hesseling AC, et al. A refined symptom-based approach to diagnose pulmonary tuberculosis in children. Pediatrics. 2006;118(5):1350-1359. https://doi.org/10.1542/ peds.2006-0519. Published November 1, 2006. Accessed June 10, 2016.

