KHÁNG INSULIN VÀ MỐI LIÊN QUAN VỚI CÁC CHỈ SỐ BMI, LIPID MÁU Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2

Abstract

Objective: This study aims to investigate the relationship between insulin resistance and BMI, lipid profile in patients with type 2 diabetes mellitus (T2DM). Methodology: A cross-sectional study was conducted on 70 patients with T2DM and 40 healthy controls. Laboratory tests included glucose, insulin, cholesterol, triglycerides, HDL-C, and BMI. The HOMA-IR index was used to define insulin resistance. Results: The prevalence of insulin resistance in the T2DM group was 82.9%, significantly higher than the 25% in the control group. Patients with insulin resistance had higher glucose (8.5 ± 2.88 mmol/L) and insulin (13.8 ± 8.39 μU/ml) levels compared to those without insulin resistance. BMI ≥ 23 was strongly associated with insulin resistance. There were no significant differences in lipid profile markers between the insulin-resistant and non-insulin-resistant groups. Conclusion: Insulin resistance is closely associated with BMI in patients with T2DM. However, in this study, insulin resistance was not significantly correlated with lipid profile markers.