STUDY ON CLINICAL AND PARACLINICAL CHARACTERISTICS AND ASSOCIATED FACTORS OF MORTALITY IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME AT THE INTENSIVE CARE UNIT, CAN THO GENERAL HOSPITAL IN 2024–2025

Thị Thanh Nhàn Nguyễn, Thị Hồng Trân Nguyễn, Thành Bích Thảo Nguyễn

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Abstract

Objectives: To investigate the clinical and paraclinical characteristics and associated factors of mortality in patients with acute respiratory distress syndrome (ARDS). Subjects and Methods: A cross-sectional descriptive study was conducted on 61 ARDS patients treated at the Intensive Care Unit, Can Tho General Hospital, from June 2024 to January 2025. Results: The mean age was 63.21 ± 14.35 years, with males accounting for 52.5%. The mean SOFA and Murray scores were 4.44 ± 3.47 and 2.30 ± 1.04, respectively. Severe ARDS accounted for 31.2% of cases. The mean PaO₂/FiO₂ ratio was 138.31 ± 52.88. Diffuse bilateral lung infiltrates on chest X-ray were observed in 39.3% of patients. The overall mortality rate was 54.1%. Factors associated with increased mortality included septic shock (OR = 3.55), multiorgan failure (OR = 9.67), SOFA score ≥2 (OR = 8.36), serum lactate >2 mmol/L (OR = 1.95), and Murray score >2.5 (OR = 3.07). Conclusions: Patients with ARDS had a relatively high mortality rate. Factors related to increased mortality included the extent of lung injury on chest X-ray, presence of septic shock, multiorgan failure, elevated blood lactate, and higher SOFA and Murray scores at admission.

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