SURVEY OF QUALITY OF LIFE IN PATIENTS WITH HEART FAILURE WITH REDUCED AND MILDLY REDUCED EJECTION FRACTION AT UNIVERSITY MEDICAL CENTER HO CHI MINH CITY

Cao Sơn Lương, Thanh Hiền Nguyễn, Uyên Phương Phạm, Thị Mỹ Danh Bùi, Thị Phương Đặng, Thị Lam Phạm, Thị Thùy Phạm

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Abstract

Objectives: To assess quality of life (QoL) in patients with heart failure (HF) with reduced and mildly reduced ejection fraction (EF) at University Medical Center Ho Chi Minh City using the Kansas City Cardiomyopathy Questionnaire (KCCQ-12), and to identify associated factors. Methods: A cross-sectional study was conducted from November 2023 to May 2024 at the Heart Failure Clinic, University Medical Center Ho Chi Minh City. A total of 191 HF patients with EF ≤49% were enrolled. Data were collected using the Vietnamese version of KCCQ-12 and clinical records. Logistic regression analysis was performed to identify factors related to QoL. Results: Among 191 patients, 113 had reduced EF (≤40%) and 78 had mildly reduced EF (41–49%). Mean total KCCQ-12 scores were 74.5 ± 16.3 in the reduced EF group and 75.3 ± 15.8 in the mildly reduced EF group, with no significant difference (p=0.705). Use of all four guideline-recommended medications was significantly associated with better QoL in the reduced EF group (OR=0.43, p=0.007), while SGLT2 inhibitors were linked to improved QoL in the mildly reduced EF group (OR=0.21, p=0.031). Conclusions: QoL in Vietnamese HF patients with reduced and mildly reduced EF was relatively good and not solely dependent on EF. Optimal medical treatment, especially SGLT2 inhibitors, is associated with improved QoL. KCCQ-12 is a useful tool for routine clinical assessment.

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References

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