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STUDY ON CHARACTERISTICS, ASSOCIATED FACTORS, AND TREATMENT OUTCOMES OF AVOCADO SOYBEAN UNSAPONIFIABLES IN PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2024–2025
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Abstract
Objectives: To describe the clinical characteristics, associated factors, and evaluate the treatment outcomes of avocado soybean unsaponifiables (ASU) in patients with primary knee osteoarthritis. Materials and methods: A cross-sectional descriptive study was conducted on patients with primary knee osteoarthritis at Can Tho University of Medicine and Pharmacy Hospital from November 2024 to March 2025. Results: Among 80 patients, males accounted for 37.5%, with a mean age of 62.3 ± 12.0 years. Patients with severe knee osteoarthritis had higher rates of diabetes mellitus, dyslipidemia, overweight/obesity, and older age compared to those with less severe disease. Patients treated with Piascledine showed improvement in pain, with the mean VAS score decreasing from 49.3 ± 19.6 mm to 25.3 ± 10.2 mm. Conclusion: A history of diabetes mellitus, dyslipidemia, overweight/obesity, and older age are factors associated with an increased risk of severe primary knee osteoarthritis. Treatment with avocado soybean unsaponifiables, using the formulation Piascledine, resulted in improved pain symptoms and knee joint function in patients with primary knee osteoarthritis
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Keywords
primary knee osteoarthritis, clinical characteristics, treatment outcome, avocado soybean unsaponifiable.
References
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