KHẢO SÁT THỰC TRẠNG SỬ DỤNG THUỐC TRONG ĐIỀU TRỊ NGOẠI TRÚ HEN PHẾ QUẢN TẠI BỆNH VIỆN ĐA KHOA THỐNG NHẤT - ĐỒNG NAI NĂM 2024

Abstract

Background: Asthma has become a global health issue with high morbidity and mortality rates. Therefore, appropriate medication use is essential to ensure effective disease control and treatment. Consequently, research on current drug use among asthma outpatients is critical. Objective: This study surveyed the status of drug use in the outpatient treatment of bronchial asthma at Thong Nhat General Hospital-Dong Nai in 2024. Methods: A cross-sectional descriptive study based on retrospective data from electronic prescriptions of asthma patients who met the inclusion criteria. Results: The sample consisted of 524 patients across 1,995 outpatient treatment episodes, with the male-to-female ratio was 2.7:1; the mean age of 56.45±15.90 years. All the patients had health insurance, with 79.77% having a health insurance coverage of 80%. The combination regimen had the highest usage rate (90.18%), with with the two-drug regimen of ICS + LABA accounting for the majority (61.89%), and the most frequently prescribed drug class was LABA (75.84%), followed by ICS (70.48%), SABA (63.81%), SAMA (52.33%), SCS (24.81%). The most frequently used drugs within the LABA, ICS, SABA, SAMA, SCS groups were formoterol (47.32%), budesonide (51.92%), fenoterol (77.69%), ipratropium (100%), methylprednisolone (71.92%), respectively. The evaluation of prescription indicators across the 1,995 prescriptions containing 8,214 drug items, showed that the average number of drugs per prescription was 4.12±2.38, 41.58% of the prescribed drug items were those included in the essential medicines list, 2.81% of the prescriptions included injectable drugs, 26.07% of the prescriptions included antibiotics, and 5.26% of the prescriptions included vitamins. Conclusion: The combination of ICS+LABA and the drug groups LABA, ICS in inhaled and oral forms are commonly prescribed to asthma outpatients. The trends of prescription indicators should be monitored and evaluated over the years to improve the effectiveness of drug use.