STUDY ON THE RELATIONSHIP BETWEEN PLASMA ADIPONECTIN LEVELS AND SOME HEMATOLOGICAL PARAMETERS IN PATIENTS WITH GASTRIC CARCINOMA
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Abstract
Objectives: To investigate the association between plasma adiponectin levels and some hematological characteristics in gastric carcinoma patients. Subjects and methods: This descriptive longitudinal study was conducted on 68 patients with histologically confirmed gastric carcinoma who underwent curative gastrectomy. Preoperative serum adiponectin levels were measured using a sandwich ELISA (FineTest). Hematological parameters were compared between two groups classified according to the median adiponectin value. Results: The low adiponectin group had significantly higher lymphocyte counts (p = 0.011), red blood cell counts (p = 0.009), and hematocrit levels (p = 0.021). Anemia was more common in the high adiponectin group (p = 0.013). No significant differences were found in neutrophil or platelet counts. Conclusion: Patients with gastric cancer who have low adiponectin levels exhibit higher lymphocyte counts, red blood cell counts, and hematocrit values; conversely, those with high adiponectin levels are more prone to anemia than the low-adiponectin group
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Keywords
Gastric carcinoma; adiponectin; hematological indices; systemic inflammation
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