STUDY ON CLINICAL AND PARACLINICAL CHARACTERISTICS AND RESULTS OF TREATMENT WITH DAPAGLIFLOZIN IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION IN CAN THO CARDIOVASCULAR HOSPITAL IN 2023 - 2025

Minh Huy Phan, Kim Sơn Trần

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Abstract

Background: Heart failure with preserved ejection fraction is a serious cardiovascular disease, greatly affecting the quality of life and increasing the medical burden. However, clinically, many doctors miss the diagnosis because this is a heterogeneous disease, leading to the detection of the disease when the heart failure stage is late, thereby increasing the medical burden. The clinical symptoms in patients with heart failure with preserved ejection fraction are very diverse and complex, so we conducted a study on the main clinical and paraclinical characteristics in the group of patients with heart failure with preserved ejection fraction at Can Tho City Cardiovascular Hospital in the period of 2023-2025. Objectives: Description of clinical and paraclinical characteristics in patients with heart failure with preserved ejection fraction. Materials and methods: Cross-sectional descriptive study of 115 patients diagnosed with heart failure with preserved ejection fraction (EF ≥ 50%) according to ESC 2021 criteria being treated at Can Tho City Heart Hospital. Results: The average age of the patients was 70.4 ± 10.5 years, with 63.48 being female. Dyspnea on exertion was the most commonly reported symptom. NYHA Class III was the most frequently observed classification. The median NT-proBNP level was 434.4 pg/ml. The most prevalent clinical phenotype was the metabolic phenotype (32.2%). Conclusions: Dyspnea on exertion was the most common symptom, and NYHA Class III was the most frequently observed classification among patients with heart failure with preserved ejection fraction (HFpEF). The clinical phenotype is equivalent to each other about the prevalence in clinical practice.

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References

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