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EVALUATION OF SERUM URIC ACID CONTROL IN PATIENS WITH METABOLIC SYNDROME TREATED WITH FEBUXOSTAT
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Abstract
Objective: To evaluate the effectiveness of febuxostat in controlling serum uric acid levels in patients with metabolic syndrome. Subjects and methods: A cross-sectional descriptive study was conducted on 33 patients aged ≥18 years diagnosed with hyperuricemia and metabolic syndrome. All patients were treated with febuxostat for 12 weeks at Hoang Tuan General Hospital, Soc Trang Province, in 2025. Results: After 12 weeks of treatment with febuxostat, the mean serum uric acid level significantly decreased from 653.0 ± 70.3 µmol/L at baseline to 337.9 ± 49.2 µmol/L (p < 0.001). The proportion of patients achieving the target uric acid level increased from 54.5% at week 4 to 97% at week 12 (p < 0.001). Conclusion: Febuxostat is effective in controlling serum uric acid levels in patients with metabolic syndrome.
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Keywords
metabolic syndrome, febuxostat, serum uric acid.
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