Article Sidebar

pdf
Date Published: 03/10/2025
Abstract Views: 177
Views pdf: 93
DOI: https://doi.org/10.51298/vmj.v554i2.15683
Issue
Vol. 554 No. 2 (2025)
Section
Các bài báo
How to Cite
Dương Minh, P., Nguyễn Văn, T., & Lê Trung, T. (2025). PULMONARY ALVEOLAR MICROLITHIASIS: A CASE REPORT AT THE NATIONAL LUNG HOSPITAL. Vietnam Medical Journal, 554(2). https://doi.org/10.51298/vmj.v554i2.15683

PULMONARY ALVEOLAR MICROLITHIASIS: A CASE REPORT AT THE NATIONAL LUNG HOSPITAL

Phương Dương Minh, Tình Nguyễn Văn, Thọ Lê Trung

Main Article Content

Abstract

Case report: A 71-year-old male patient was admitted to the hospital due to dyspnea. His illness had progressed over two weeks with symptoms of productive cough with white sputum, no hemoptysis, and worsening shortness of breath on exertion. He initially sought examination and treatment at a local hospital, where he was diagnosed with pneumonia with suspected pneumoconiosis, and was then transferred to the National Lung Hospital for further diagnosis and treatment. Chest computed tomography (CT) imaging revealed diffuse ground-glass opacities in the lung parenchyma with calcifications. Tests for bacteria, fungi, and tuberculosis were negative. The patient underwent a lung biopsy under CT guidance, and histopathological examination confirmed a diagnosis of pulmonary alveolar microlithiasis (PAM).

Article Details

Keywords

Pneumonia, pulmonary alveolar microlithiasis (PAM)

References

1. Shaw BM, Shaw SD, McCormack FX (2020). Pulmonary Alveolar Microlithiasis. Semin Respir Crit Care Med.;41(2):280-287. doi:10.1055/s-0040-1702211.
2. Kosciuk P, Meyer C, Wikenheiser-Brokamp KA, McCormack FX (2020). Pulmonary alveolar microlithiasis. Eur Respir Rev. ;29(158):200024. doi:10.1183/16000617.0024-2020.
3. Corut A, Senyigit A, Ugur SA, et al (2006). Mutations in SLC34A2 Cause Pulmonary Alveolar Microlithiasis and Are Possibly Associated with Testicular Microlithiasis. Am J Hum Genet;79(4):650-656. doi:10.1086/508263.
4. Huqun null, Izumi S, Miyazawa H, et al (2007). Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis. Am J Respir Crit Care Med.;175(3):263-268. doi:10.1164/rccm.200609-1274OC.
5. Mariotta S, Ricci A, Papale M, et al (2004). Pulmonary alveolar microlithiasis: report on 576 cases published in the literature. Sarcoidosis Vasc Diffuse Lung Dis Off J WASOG ;21(3):173-181.
6. Caffrey PR, Altman RS(1965). Pulmonary alveolar microlithiasis occurring in premature twins. J Pediatr ;66:758-763. doi:10.1016/s0022-3476(65)80012-9
7. Krishnakurup J, Abdelsayed G (2011). The calcareous lung. Mayo Clin Proc.;86(2):85. doi:10.4065/mcp.2010.0274
8. Corut A, Senyigit A, Ugur SA, et al (2006). Mutations in SLC34A2 Cause Pulmonary Alveolar Microlithiasis and Are Possibly Associated with Testicular Microlithiasis. Am J Hum Genet.;79(4):650-656. doi:10.1086/508263
9. Akella A, Deshpande SB (2013). Pulmonary surfactants and their role in pathophysiology of lung disorders. Indian J Exp Biol.;51(1):5-22.
10. Castellana G, Castellana G, Gentile M, Castellana R, Resta O (2015). Pulmonary alveolar microlithiasis: review of the 1022 cases reported worldwide. Eur Respir Rev.;24(138):607-620. doi:10.1183/16000617.0036-2015.