INVESTIGATION OF FACTORS ASSOCIATED WITH NEWLY DIAGNOSED CHRONIC KIDNEY DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AT THE NATIONAL HOSPITAL OF ENDOCRINOLOGY

Hữu Tài Vũ, Thị Thu Hương Nguyễn, Gia Tuyển Đỗ

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Abstract

Objective: To determine the prevalence of newly diagnosed chronic kidney disease (CKD) and identify associated factors in patients with type 2 diabetes mellitus (T2DM) at the National Hospital of Endocrinology. Subjects and Methods: A cross-sectional descriptive study was conducted on 350 patients previously diagnosed with T2DM who presented to the National Hospital of Endocrinology between September 2024 and June 2025. Results: The prevalence of newly diagnosed CKD was 10.9%. The majority of cases (98.3%) were identified at early stages, with stage 2 being the most common (51.7%). Poor blood pressure control, elevated HbA1c, and longer duration of diabetes were significantly associated with newly diagnosed CKD. Conclusion: Although the detection rate of CKD among patients with T2DM was relatively low, most cases were identified at an early stage. These findings underscore the importance of regular screening using both estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (uACR) to ensure early detection and avoid missed diagnoses.

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References

Gaddy A, Elrggal M, Madariaga H, et al. Diabetic Kidney Disease. Disease-a-month : DM. 2025;71(4):101848.
2. Levin A, Ahmed S B, et al Carrero J J. Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease: known knowns and known unknowns. Kidney international. 2024;105(4):684-701.
3. Nguyễn Cao Thắng, Đặng Bảo Trâm, Phạm Quốc Toản. Nghiên cứu nguy cơ tiến triển bệnh thận mạn tính giai đoạn cuối và mối liên quan với mức độ kiểm soát glucose máu, HbA1c ở bệnh nhân đái tháo đường típ 2. Tạp chí Y học Quân sự. 2024;371:27-31.
4. Suh SH, Oh TR, Choi HS, et al. Serum triglycerides level is independently associated with renal outcomes in patients with non-dialysis chronic kidney disease: Results from KNOW-CKD study. Frontiers in nutrition. 2022;9:1037618.
5. Wu Nianwei, Xia Jing, Chen Sen, et al. Serum uric acid and risk of incident chronic kidney disease: a national cohort study and updated meta-analysis. Nutrition & Metabolism. 2021;18(1):94.
6. Trịnh Quốc Khởi, Dương Phúc Lam, Phạm Thị Nhã Trúc. Tỷ lệ đái tháo đường týp 2 có biến chứng thận và thực trạng phòng, chống biến chứng thận ở bệnh nhân đái tháo đường týp 2 tại Bệnh viện Đa Khoa Cái Nước năm 2022-2023. Tạp chí Y học Việt Nam. 2023;531(1B).
7. Alidrisi DA, Alidrisi HA, Reman KA, et al. Prevalence of and Factors Associated With Incidental Chronic Kidney Disease in Patients Newly Diagnosed With Type 2 Diabetes Mellitus. Cureus. 2025;17(2).
8. Calvo-HJ, Martín-HB, Morales G, et al. Chronic kidney disease prevalence and cardiovascular risk in a cohort of patients with type 2 diabetes followed for 10 years in Badajoz (Spain). An observational study. Primary Care Diabetes. 2021;15(2):391-396.