RESULT OF PLATELETPHERESIS AND ANTI-PLATELET MEDICATION IN TREATMENT OF ESSITIAL THROMBOCYTHEMIA AT VIETNAM - CZECH FRIENDSHIP HOSPITAL IN 2017 - 2019

Van Phong Hoang 1,, Manh Quan Ngo 2, Ngoc Dung Nguyen 2, Thi Thu Huyen Nguyen 3, Tuan Viet Pham 4
1 Center for Hematology - Blood Transfusion, Vietnam- Czech friendship hospital
2 National Institute of Hematology - Blood Transfusion
3 Internal medical department, Vietnam- Czech friendship hospital
4 Health Strategy and Policy Institute

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Tóm tắt

The study was carried out in 56 essential thrombocytosis patients admitted to Vietnam - Czech hospital in Hai Phong city from 01/01/2017 to 06/2019. Subject: Investigation of the effectiveness of plateletpheresis and anti - platelet medication treatment (combined with hydroxyurea) in essential thrombocytosis. Method: prospective study with clinical intervention. Results: 1. The effectiveness of plateletpheresis. 1.1. Most of patients have improvement regarding symptoms related to microvascular stasis due to thrombocytosis (reduced from 58,3% to 31,8% with p < 0,05). 1.2. After 24 hours of plateletpheresis, platelet count reduced from 1,340 G/l to 736 G/l. 2. The effectiveness of anti-platelet medication after plateletpheresis: after 2 weeks of treatment, most of patients have significant improvements regarding symptoms related to microvascular stasis due to thrombocytosis (reduced from 31,8% to 3,8%).

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Tài liệu tham khảo

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