HYPERTHYROIDISM CAUSED BY HASHIMOTO’S THYROIDITIS IN CHILDREN

Nguyễn Trọng Thành, Vũ Chí Dũng

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Abstract

Hashimoto’s thyroiditis is one of the most common acquired thyroid disorders with goiter in children. It is characterized clinically by gradual hypothyroidism, however, hyperthyroidism sometimes can be one of clinical manifestations in early course of disease (Hashitoxicosis). Aims: to describe clinical characteristics, biochemical tests and treatment in 39 patients diagnosed with Hashitoxicosis. Subjectives: Patients diagnosed with Hashitoxicosis treated in Endocrinology – Metabolism – Genetic Department at the Vietnam National Children’s Hospital from January 2018 to December 2019. Methods: case series study. Results: there were totally 39 patients diagnosed with Hashitoxicosis. Their mean age was 9.75 ± 2.22 years. Common complaints were goiter. All patients were treated with Thiamazole (Thyrozol) and 26 out of 39 patients received Propranolol. Conclusions: Goiter was the most common complaint. Morbidity rate was higher in girls than boys. It is essential to identify the cause in approaching to a patient who presents signs and symptoms of hyperthyroidism.

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References

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