EFFECTIVENESS OF ANTIMICROBIAL STEWARSHIP PROGRAM ON TREATMENT OF PERITONITIS AT A HOSPITAL IN HOCHIMINH CITY

Võ Duy Thông, Trần Thiên Tân

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Abstract

Objective: To evaluate the role of antimicrobial stewardship program (ASP) in the appropriateness of anitibiotic use in treatment of peritonitis. Methods: A before and after cross–sectional study was conducted on medical records of patients diagnosed with peritonitis from 10/2018 to 3/2019 (before ASP) and from 10/2019 to 3/2020 (after ASP) at a hospital in Hochiminh City. Patient medical records were collected for data analysis including demographics, isolated organisms, antibiotic use, and treatment outcomes. The appropriateness of antibiotic use was assessed based on National antibiotic, SIS 2017. The effectiveness of ASP on treatment of cholecystitis was evaluated by comparing the rate of antibiotic appropriateness and treatment outcomes before and after applying ASP. Results: There were 104 medical records before ASP and 107 ones after ASP included in this study. The median age of patients was 40-44; 53.3-55.8% was man. E. coli (63.5%) and K. pneumoniae (11.5%) were the most common isolated organisms. The rate of appropriate antibiotic use in empiric treatment increased from 9.6% to 43.9% (p = 0,04) based on SIS 2017 guideline. 99% of patients recovered after treatment in both periods – before anf after ASP. Conclusion: The antimicrobial stewardship program increases the rate of appropriate antibiotic use in treatment of peritonitis.

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