ASSOCIATIONS BETWEEN OVERWEIGHT, OBESITY, AND NEW-ONSET DIABETES AFTER RENAL TRANSPLANTATION

Nguyễn Đức Thuận, Đặng Thành Chung

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Abstract

Objectives: To study the ratio of overweight and obesity and the relationship with new-onset diabetes after three months of renal transplantation. Subjects and methods: ncluding 508 patients with kidney post-transplant more than three months who are followed up and treated at Viet Duc University Hospital from September 2017 to April 2018. All patients volunteered to participate in the study. Clinically examined, measured the height and weight of participants. Collect blood samples of recipients in the morning before eating and taking immunosuppressants. Carry out an oral glucose tolerance test (OGTT) when indicated. Diagnosis of overweight, obesity, pre-diabetes, and diabetes mellitus after kidney transplantation according to standards. Results: The overweight and obese group accounted for 30.12% of the study patients. The proportion of patients diagnosed with NODAT who were overweight and obese was statistically significantly higher than those who were not overweight and obese, p = 0.003. The risk of developing NODAT in overweight and obese patients is 2.13 (95%: 1.29-3.53) higher than in obese non-overweight and obese patients. Conclusion: This study shows that the incidence and risk of NODAT is more heightened in overweight and obese patients, so to avoid post-transplant failure and related complications, it seems reasonable to emphasize that those who are renal transplants should maintain an average weight.

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References

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