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Date Published: 08/06/2021
Abstract Views: 248
Views PDF: 183
DOI: https://doi.org/10.51298/vmj.v500i1.332
Issue
Vol. 500 No. 1 (2021)
Section
Các bài báo
How to Cite
Anh Tuấn, T. . (2021). EVALUATION THE COMPLICATIONS OF BRIDGING THERAPY IN ISCHEMIC STROKE PATIENTS. Vietnam Medical Journal, 500(1). https://doi.org/10.51298/vmj.v500i1.332

EVALUATION THE COMPLICATIONS OF BRIDGING THERAPY IN ISCHEMIC STROKE PATIENTS

Trần Anh Tuấn

Main Article Content

Abstract

Purpose: The aim of this study was to evaluate the complications associated with brain artery recanalization using combined intravenous thrombolysis and mechanical thrombectomy. Materials and methods: The patients with acute ischemic stroke who were treated with 0.9 mg of thrombolytic agent per kilogram of body weight plus mechanical thrombectomy less than 270 minutes after the onset of ischemic stroke. We evaluated the complications after the treatment, especially cerebral hemorrhage after reperfusion. Result: Among 35 patients, the rate of successful recanalization (TICI 2b-c) was 94%. Good recovery rate at 90-day follow-up was 62,9% (mRS 0-2). The hemorrhagic transformation rate was 37,1%, asymptomatic hemorrhage was predominant and appeared in 10 out of 13 patients (76.9%). In addition, other complications occurred such as pneumonia (5,8%), renal failure (5.85%) and early neurological deterioration (8.6%). Conclusion: Hemorrhagic transformation was a frequent complication after intravenous thrombolysis with mechanical thrombectomy, but this combined therapy was still an effective treatment in acute ischemic stroke patients with large vessel occlusions.

Article Details

Keywords

Ischemic stroke, thrombolysis, mechanical thrombectomy, hemorrhagic transformation

References

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