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Ngày xuất bản: 18/04/2023
Số lượt xem tóm tắt: 87
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DOI: https://doi.org/10.51298/vmj.v525i1.5060
Số xuất bản
Tập 525 Số 1 (2023): Vietnam Medical Association
Chuyên mục
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Trích dẫn bài báo
Quang Duc, N. ., Phuong Tien, N. ., Ngoc Lam, V. ., & Diep Linh, L. . (2023). LARGE CELL UNDIFFERENTIATED CARCINOMA OF PAROTID GLAND: A CASE REPORT AND LITERATURE REVIEW. Tạp Chí Y học Việt Nam, 525(1). https://doi.org/10.51298/vmj.v525i1.5060

LARGE CELL UNDIFFERENTIATED CARCINOMA OF PAROTID GLAND: A CASE REPORT AND LITERATURE REVIEW

Quang Duc Nguyen 1, Phuong Tien Nguyen 1, Ngoc Lam Vu 1, Diep Linh Le 1,
1 Craniofacial and Plastic Surgery Center - 108 Military Central Hospital

Nội dung chính của bài viết

Tóm tắt

Large cell undifferentiated carcinoma of parotid gland is a rare disease of salivary gland cancer accounting about 1%, however, it has high malignancy and very poor prosgnosis. We report a clinical case with symptoms of left parotid gland tumor, rapid growth , invasive skin and superficial ulceration . The differential diagnosis is difficult between parotid adenocarcinoma and skin cancer or metastatic cervical lymphoma. The patient underwent extensive surgical resection of the lesion, radical cervical lymphadenectomy, and reconstruction with local flaps. The definitive diagnosis after surgery: large cell undifferentiated carcinoma of the left parotid gland stage IV (pT4aN0M0). The patient did not receive early radiation therapy, therefore local recurrence and distal metastasis, and death 6 months after surgery.

Chi tiết bài viết

Từ khóa

large cell undifferentiated carcinoma, LCUC, salivary cancer

Tài liệu tham khảo

1. Schrank TP, Zhan KY, and Lentsch EJ (2017). Predictors of outcomes in large cell undifferentiated carcinoma of the major salivary glands: Large Cell Undifferentiated Carcinoma. The Laryngoscope , 127 ( 2 ), 372-376.
2. Wang C.-P., Chang Y.-L., Ko J.-Y. and associates. (2004). Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer , 101 ( 9 ), 2020-2027.
3. Robert L.Ferris ENM (2007). Large cell carcinoma. Salivary gland disorders . 79.
4. Nagao T., Sugano I., Ishida Y. et al. (2000). Primary Large-Cell Neuroendocrine Carcinoma of parotid gland: Immunohistochemical and Molecular Analysis of Two Cases. Mod Pathol , 13 ( 5 ), 554-561.
5. Geiger JL, Ismaila N., Beadle B. et al. (2021). Management of Salivary Gland Malignancy: ASCO Guideline. J Clin Oncol , 39 ( 17 ), 1909-1941.
6. Sood S., McGurk M., and Vaz F. (2016). Management of Salivary Gland Tumours: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol , 130 ( S2 ), S142-S149.
7. Hosni A., Huang SH, Goldstein D. et al. (2016). Outcomes and prognostic factors for major salivary gland carcinoma following postoperative radiotherapy. Oral Oncol , 54 , 75-80.
8. Prekazi-Loxha M., Rusinovci S., and Stubljar D. (2019). Rates of tumor recurrences and metastases after surgical removal of malignant salivary gland tumours throughout 5-years of follow-up: A retrospective single-centre study. Oral Maxillofac Surg Cases , 5 ( 3 ), 100105.