BIẾN CHỨNG XƠ GAN Ở BỆNH NHÂN XƠ GAN MẤT BÙ CÓ ĐÁI THÁO ĐƯỜNG

Abstract

Background: The prevalence of diabetes mellitus in patients with cirrhosis ranges from 14−71 %. Diabetes mellitus is associated with an increased risk of hepatic complications and death in patients with liver cirrhosis. Objectives: To investigate the complications of cirrhosis in patients with decompensated cirrhosis have diabetes mellitus. Method: Descriptive cross-sectional study was carried out at Bach Mai hospital between August 2021 and Octocber 2022, in which 200 patients with decompenstated cirrhosis were recruited. Results: In all, 72 patients had diabetes mellitus (36%).  In the group with diabetes mellitus, the most common complication of decompenstated cirrhosis is ascites  (61.6%). Patients with diabetes mellitus had a significantly higher prevalence (29.2% vs 10.2%; P = 0.03) of hepatic encephalopathy than patients without diabetes mellitus. However, there were no significant differences between the two groups in the prevalence of ascites, Spontaneous bacterial peritonitis, hepatorenal syndrome and variceal hemorrhage. Patients with diabetes mellitus had higher prevalence (27.8% vs 15.6%; P = 0.039)  of infection than those without diabetes mellitus. Conclusion: the prevalence of diabetes in decompenstated cirrhosis is 36%. Diabetes mellitus is associated with a higher prevalence of hepatic encephalopathy in patients with decompenstated cirrhosis.