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Date Published: 05/07/2023
Abstract Views: 675
Views PDF: 284
DOI: https://doi.org/10.51298/vmj.v527i2.5905
Issue
Vol. 527 No. 2 (2023)
Section
Các bài báo
How to Cite
Bạch , V. D., Nguyễn, T. M. L., Hoàng, T. L. H., Nguyễn, T. H. H., Trần, T. T. T., & Nguyễn, T. L. H. (2023). ANALYSIS OF DRUG-RELATED PROBLEMS IN PRESCRIBING ANTI-CANCER DRUGS AT A SPECIALIZED ONCOLOGY HOSPITAL. Vietnam Medical Journal, 527(2). https://doi.org/10.51298/vmj.v527i2.5905

ANALYSIS OF DRUG-RELATED PROBLEMS IN PRESCRIBING ANTI-CANCER DRUGS AT A SPECIALIZED ONCOLOGY HOSPITAL

Văn Dương Bạch 1, Thị Mai Lan Nguyễn1, Thị Lê Hảo Hoàng1, Thị Hồng Hạnh Nguyễn2, Thị Thu Trang Trần2, Thị Liên Hương Nguyễn2,
1 Hanoi Oncology Hospital
2 Hanoi University of Pharmacy

Main Article Content

Abstract

Objective: To determine the frequency and types of drug-related problems (DRPs) related to prescribing of anti-cancer drugs. Subject and method: A cross-sectional descriptive study was conducted among inpatients who were diagnosed with 1 of the 5 most common cancers in Vietnam at a specialized oncology hospital and were discharged between June 1st 2022 and June 15th 2022. Clinical pharmacist reviewed the cycles of anti-cancer drug to identify DRPs with standard protocols in the literature, then classified them according to the Ministry of Health guidance at Decision 3547/QĐ-BYT. Results: A total of 2236 DRPs were detected in 791 cycles out of 1027 treatment cycles (77.0%). The most prevalent DRPs were dosing problems (31.7%). Drug selection accounted for 30.4%, most of which were inappropriate route/dosing forms (20.1%). The DRPs related to treatment duration and incomplete prescription information accounted for similar proportions (19.2% and 18.7% respectively). DRPs related to FOLFOX and Oxaliplatin - Capecitabin/UFT protocol accounted for the highest proportions (17.1% and 15.2% respectively); the majority of DRPs were related to chemotherapy drugs (91.4%). Conclusion: DRPs involving anti-cancer drug prescribing and selection were considerably common. Further studies are needed to determine the extent of the clinical impact of DRPs, and appropriate interventions should be carried out to minimize DRPs in patients using cancer drugs.

Article Details

Keywords

Drug-related problems, prescriptions, cancer drugs.

References

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