KẾT QUẢ SỬ DỤNG KHỐI TẾ BÀO ĐƠN NHÂN CHỨA TẾ BÀO GỐC TỪ TỦY XƯƠNG TỰ THÂN ĐIỀU TRỊ TRẺ BẠI NÃO DO THIẾU OXY TẠI BỆNH VIỆN VINMEC TIMES CITY

Abstract

Objective: Research using single - nuclear cell masses containing stem cells from autologous bone marrow in treating children with cerebral cerebral palsy due to  Brain hypoxia at birth was accepted at the Ministry of Science and Technology in September 2018. Initial results showed safety and evidence of effectiveness. The objective of this study is to confirm the effectiveness of a single -nuclear cell masses containing stem cells from autologous bone marrow on a larger sample size in children with cerebral palsy due to lack of oxygen at birth. Subjects and methods: This is a restrospective-perspective combined  conducted in more than 50 cerebral palsy patients due to asphyxia that has been infused the single cell masses containing stem cells from the autologous bone marrow at Vinmec International Hospital. Effectiveness is evaluated at 6 months, 12 months after the first transfusion using Gross Motor Function Measure 88 Items (GMFM-88) and Modified Ashworth Score (MAS). Results: The gross motor function is measured by GMFM-88 and the level of muscle tone are measured by modified Ashworth improved statistical significance at 6 months and 12 months after transfusion of single - nuclear cell masses containing stem cells from autologous bone marrow. Conclusion: Using single -nuclear cell masses containing stem cells from the autologous bone marrow in the treatment of children with cerebral palsy due to  asphyxia is effective.