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Date Published: 25/08/2023
Abstract Views: 320
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DOI: https://doi.org/10.51298/vmj.v529i1.6262
Issue
Vol. 529 No. 1 (2023)
Section
Các bài báo
How to Cite
Phí, T. T. A., Nguyễn, T. L. H., Vũ, Đình H., Đào, T. T. P., & Lê, V. M. (2023). CORRELATION BETWEEN MORPHOKINETIC PARAMETERS OF DAY 3 EMBRYOS AND IMPLANTATION CAPABILITY IN FROZEN BLASTOCYST TRANSFER CYCLES. Vietnam Medical Journal, 529(1). https://doi.org/10.51298/vmj.v529i1.6262

CORRELATION BETWEEN MORPHOKINETIC PARAMETERS OF DAY 3 EMBRYOS AND IMPLANTATION CAPABILITY IN FROZEN BLASTOCYST TRANSFER CYCLES

Thị Tú Anh Phí1,, Thị Liên Hương Nguyễn1, Đình Hợp Vũ1, Thị Thúy Phượng Đào2, Văn Mạnh Lê3
1 Tam Anh General Hospital in Hanoi
2 HMU
3 Bac Ninh Obstetrics and Children Hospital

Main Article Content

Abstract

Objective: To determine the correlation between the morphokinetic parameters of day-3 embryos and implantation capability in frozen blastocyst transfer cycles. Subjects and research methods: A retrospective cohort study was conducted on 383 good quality blastocysts of frozen embryo transfer cycles from March 2020 to December 2022 at Tam Anh General Hospital. The study evaluated the differences in parameters including tPNa, tPNf, t2 – t8, cc1, cc2, cc3, s2, s3, and abnormal division (direct, reverse cleavage) between implant and non-implant groups. The decision tree algorithm was used to build a hierarchical model of implantation, ROC was performed to evaluate the model’s prognostic value . Results: Analysis of morphokinetic parameters enabled us to develop a hierarchical model that places the direct cleavage, tPNa, and cc1 as the variables with the best prognosis of implantation. The AUC value of the model was 0.641. Conclusion: This retrospective study suggested that morphokinetic parameters at the early cleavage stage  can be used adjunctively with traditional morphology to select embryos with higher implantation potential.

Article Details

Keywords

morphokinetic, implantation, timelapse, frozen blastocyst transfer

References

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