HIỆU QUẢ ĐIỀU TRỊ LOÉT DẠ DÀY TÁ TRÀNG TẠI BỆNH VIỆN ĐA KHOA TỈNH TRÀ VINH

Abstract

Objectives: rate of patients with gastrointestinal bleeding in each disease group. Regimens, proton bomb inhibitors are applied in gastrointestinal bleeding. Results of treatment of gastric and duodenal ulcers. Materials and methods: retrospective study, from January 2020 to the end of April 2020, at the Department of Internal Medicine General - Hospital of Tra Vinh. Select all medical records, study the proportion of people with gastrointestinal bleeding in each group of diseases. Regimens, proton bomb inhibitors are applied in gastrointestinal bleeding on medical records. Exclude patients who stop taking medication for other reasons (example: surgery), transfer to hospital or death and abandonment of treatment or escape from hospital. Use Microsoft Excel 2013. Results: the ratio of gastrointestinal bleeding compared to the total number of cases, gastric ulcer accounted for the highest rate (84.09%), the lowest was gastritis and gastric ulcer accounted for 4.55%. Gastrointestinal bleeding complications again accounted for a high rate of 68.52%, 66.67%, respectively, especially in peptic ulcer combined with gastrointestinal bleeding up to 100.00%. The regimen of low-dose proton pump inhibitors (using a dose of 80 mg/day, slow intravenous injection (rabeprazole 40 mg/day). After that, taking a dose of 40 mg/day) accounted for 36.36%, lower than the regimen high dose 63.64%. In the high-dose regimen, intravenous infustion of 8 mg/hour (rabeprazole 4 mg/hour) is recommended over 72 hours. After 3 days of continued treatment with proton pump inhibitors, an oral dose of 40 mg/day accounted for 34.09%. In the case of high-dose regimens, an intravenous infustion of 8 mg/hour (rabeprazole 4 mg/hour) for 72 hours. After 3 days of continued treatment with proton pump inhibitors, intravenous infusion of 40 mg x 5 times/day (rabeprazole 20 mg x 5 times/day), then the standard dose of 40 mg/day accounted for the lowest. 6.82%). In 235, peptic ulcers disease using proton pump inhibitors, 100.00% of the tablets were discharged in the state of improvement and reduction. Conclusions: the ratio of gastrointestinal bleeding compared to the total number of gastrointestinal bleeding, gastric ulcer accounted for the highest rate (84.09%). High-dose regimen, which accounts for the highest rate of use, in the treatment of gastrointestinal bleeding complications due to peptic ulcer disease (63.64%). Regarding the results of treatment, the rate of treatment and reduction is 100%.