TỔN THƯƠNG DA TRONG BỆNH MÔ BÀO LANGERHANS Ở TRẺ SƠ SINH: NHÂN MỘT TRƯỜNG HỢP

Abstract

Introduction: Langerhans cell histiocytosis is a rare histiocytic disorder. Histiocytes accumulate in one or more organs, leading to a variable clinical presentation of disease, in which cutaneous manifestations is the most common. Cutaneous findings are found such as seborrheic dermatitis-like lesions with petechiae/hemorrhage lesions, eczematous lesions, papules/nodules/masses and several rare manifestations. We report a case of neonatal LCH with multiple red-brown cutaneous nodules and papules spread over his body. He was diagnosed LCH with biopsy-proven Langerhans Cell Histiocytosis. Clinical case: A full-term male neonate at 1 day of age, with normal birth weight and vaginal delivery, had multiple red-brown cutaneous nodules and papules on the head, face, trunk, palms and erythematous macules on the belly, extremities. He was done blood sample tests, TORCH, imaging studies with normal results and done biopsy with result: Langerhans Cell Histiocytosis. Combining of published medical research with cutaneous manifestations and proven biopsy, we diagnosed this neonate suffering from Hashimoto-Pritzker congenital self-healing histiocytosis, a rare congenital cutaneous LCH.