BÁO CÁO CA LÂM SÀNG UNG THƯ CỔ TỬ CUNG GIAI ĐOẠN DI CĂN ĐIỀU TRỊ BẰNG PHÁC ĐỒ HÓA CHẤT KẾT HỢP THUỐC ỨC CHẾ ĐIỂM KIỂM SOÁT MIỄN DỊCH
Nội dung chính của bài viết
Tóm tắt
Trong kỷ nguyên của thuốc miễn dịch, phác đồ hóa chất kết hợp Pembrolizumab đã trở thành điều trị tiêu chuẩn mới trong ung thư cổ tử cung (UTCTC) giai đoạn tái phát, di căn. Chúng tôi báo cáo một trường hợp bệnh nhân nữ 62 tuổi, chẩn đoán UTCTC giai đoạn FIGO IVB được điều trị bằng phác đồ này và đạt được kết quả ấn tượng.
Chi tiết bài viết
Từ khóa
Ung thư cổ tử cung, Liệu pháp miễn dịch, Pembrolizumab.
Tài liệu tham khảo
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7. https://www.keytruda.com/how-does-keytruda-work/
8. Research C for DE and FDA approves pembrolizumab combination for the first-line treatment of cervical cancer. FDA. Published online January 31, 2022.
9. Tewari KS, Sill MW, Penson RT, et al. Final Overall Survival of the Phase III Randomised Trial of Chemotherapy with and without Bevacizumab for Advanced Cervical Cancer: An NRG Oncology/Gynecologic Oncology Group Study. Lancet Lond Engl. 2017;390(10103):1654-1663.
2.https://gco.iarc.fr/today/data/factsheets/populations/704-viet-nam-fact-sheets.pdf
3. Colombo N, Dubot C, Lorusso D, et al. Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer. N Engl J Med. 2021;385(20):1856-1867.
4. Long HJ, Bundy BN, Grendys EC, et al. Randomized phase III trial of cisplatin with or without topotecan in carcinoma of the uterine cervix: a Gynecologic Oncology Group Study. J Clin Oncol Off J Am Soc Clin Oncol. 2005;23(21):4626-4633.
5. Moore DH, Blessing JA, McQuellon RP, et al. Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol Off J Am Soc Clin Oncol. 2004;22(15):3113-3119.
6. Monk BJ, Sill MW, McMeekin DS, et al. Phase III Trial of Four Cisplatin-Containing Doublet Combinations in Stage IVB, Recurrent, or Persistent Cervical Carcinoma: A Gynecologic Oncology Group Study. J Clin Oncol. 2009; 27(28):4649-4655.
7. https://www.keytruda.com/how-does-keytruda-work/
8. Research C for DE and FDA approves pembrolizumab combination for the first-line treatment of cervical cancer. FDA. Published online January 31, 2022.
9. Tewari KS, Sill MW, Penson RT, et al. Final Overall Survival of the Phase III Randomised Trial of Chemotherapy with and without Bevacizumab for Advanced Cervical Cancer: An NRG Oncology/Gynecologic Oncology Group Study. Lancet Lond Engl. 2017;390(10103):1654-1663.