EVALUATING GLOMERULAR FILTRATION RATE IN LIVING KIDNEY DONORS IN VIET DUC HOSPITAL

Tóm tắt

Summary: One of the most important goals of kidney transplantation from a living kidney donor is to ensure that the function of the transplanted kidney as well as to preserve the function of the kidney donor. An ideal GFR test that ensures high accuracy, simplicity, safety, and economic efficiency is 24-hour Creatinine clearance in the assessment of living kidney donor. Objective: To achieve that, the evaluation of GFR in living kidney donors. Patients and Methods: Retrospective study (retrospective from January 2022 to December 2022. Research variables : sex, age, age group, BMI, arterial blood pressure. Evaluating Glomerular Filtration Rate in living kidney donors. CrCl 24h of each age group, CrCl 24h distribution by age groups in percentiles, Serum creatinine concentration, CrCl 24h distribution by BMI, Height, Weight groups.  Results: in this study including 65 male and 73 female, accounts for 47.1% and 52.9%, respectively. the average age of 34.283 ± 7.605. The age groups distribution of this study population is mostly focused on the under 40 age groups (82.6%). The differences of height, weight, BMI, BSA between the two sexes are statistically significant (p < 0.05). The BMI difference is not a statistically significant between male and female (p > 0.05). CrCl24h (ml/min) (uncorrected after BSA) average is 106.964 ± 11.106 (minimum: 77.845, maximum: 136.503). The differences in ClCr24h by sexes, BMI groups, height groups, and weight groups of living kidney donors are statistically significant when CrCl24h (ml/min) is not corrected after BSA (p < 0.05). After corrected, the average CrCl24h is 113.071 ± 9.747 (ml/min/1.73m²) (minimum: 91.000, maximum: 140.000), The differences in ClCr24h by sexes, BMI groups, height groups, and weight groups are not statistically significant anymore (p > 0.05). The difference of CrCl 24h between age groups is not statistically significant (p > 0.05). Conclusion: CrCl24h (ml/min) average is the average CrCl24h is 113.071 ± 9.747 (ml/min/1.73m2) (minimum: 91.000, maximum: 140.000), The differences in ClCr24h by sexes, BMI groups, height groups, and weight groups are not statistically significant anymore.